1344997-44-9

Upstream product

• 15126-06-4 methyl 3-iodo-4-hydroxybenzoate 
• 156001-68-2 methyl 3-cyano-4-hydroxybenzoate 
• 156001-69-3 methyl 3-cyano-4-(((trifluoromethyl)sulfonyl)oxy)benzoate 
• 288251-99-0 3-cyano-4-(2-methylpropyl)benzoic acid 
• 1260024-46-1 2-{2-ethyl-3-[(E)-2-(methyloxy)ethenyl]phenyl}-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 1258440-90-2 5-(5-amino-1,3,4-thiadiazol-2-yl)-2-(2-methylpropyl)benzonitrile 
• 1034689-19-4 methyl 3-cyano-4-(2-methylpropyl)benzoate 

Downstream Products

• 1344997-47-2 ethyl 1-[2-(3-{5-[3-cyano-4-(2-methylpropyl)phenyl]-1,3,4-thiadiazol-2-yl}-2-ethylphenyl)ethyl]-4-piperidinecarboxylate 
• 1344997-46-1 methyl 1-[2-(3-{5-[3-cyano-4-(2-methylpropyl)phenyl]-1,3,4-thiadiazol-2-yl}-2-ethylphenyl)ethyl]-3-azetidinecarboxylate 
• 1344997-45-0 5-{5-[2-ethyl-3-(2-oxoethyl)phenyl]-1,3,4-thiadiazol-2-yl}-2-(2-methylpropyl)benzonitrile 
• 1344996-75-3 1-[2-(3-{5-[3-cyano-4-(2-methylpropyl)phenyl]-1,3,4-thiadiazol-2-yl}-2-ethylphenyl)ethyl]-L-proline 
• 1344995-84-1 1-[2-(3-{5-[3-cyano-4-(2-methylpropyl)phenyl]-1,3,4-thiadiazol-2-yl}-2-ethylphenyl)ethyl]-4-piperidinecarboxylic acid 
• 1344995-82-9 1-[2-(3-{5-[3-cyano-4-(2-methylpropyl)phenyl]-1,3,4-thiadiazol-2-yl}-2-ethylphenyl)ethyl]-3-azetidinecarboxylic acid 

Relevant academic research and scientific papers

COMPOUNDS AS AGONISTS OF S1P1 RECEPTORS

Compounds of formula (I), processes for their preparation, pharmaceutical compositions containing them and their use in the treatment of diseases mediated by S1P1 receptors.