13450-67-4

Basic information

• Product Name: 4-(2-PIPERIDINOETHYL) PYRIDINE
• Synonyms: 4-(2-piperidinoethyl)-pyridin;4-(beta-piperidinoethyl)pyridine;4-(2-PIPERIDINOETHYL) PYRIDINE;4-[2-(piperidyl)ethyl]pyridine;4-(2-(Piperidin-1-yl)ethyl)pyridine
• CAS NO: 13450-67-4
• Molecular Formula: C₁₂H₁₈N₂
• Molecular Weight: 190.28
• EINECS: 236-607-4
• Mol File: 13450-67-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 296.2 °C at 760 mmHg
• Flash Point: 132.9 °C
• Appearance: /
• Density: 1.006 g/cm³
• Vapor Pressure: 0.00146mmHg at 25°C
• Refractive Index: 1.531
• PKA: 8.92±0.10(Predicted)
• CAS DataBase Reference: 4-(2-PIPERIDINOETHYL) PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-PIPERIDINOETHYL) PYRIDINE(13450-67-4)
• EPA Substance Registry System: 4-(2-PIPERIDINOETHYL) PYRIDINE(13450-67-4)

Safety Data

• Hazardous Substances Data: 13450-67-4(Hazardous Substances Data)

Usage

General Description

4-(2-piperidinoethyl) pyridine is a chemical compound with the formula C13H18N2. It is a derivative of pyridine with a piperidine group attached to the nitrogen atom. 4-(2-PIPERIDINOETHYL) PYRIDINE is commonly used in organic synthesis as a building block for various pharmaceuticals and agricultural chemicals. It is also used as a ligand in coordination chemistry and as a precursor for the synthesis of other functionalized pyridine derivatives. Additionally, 4-(2-piperidinoethyl) pyridine has been investigated for its potential biological activities, including its antifungal and antimicrobial properties. Overall, this chemical compound has numerous applications in the field of organic chemistry and pharmaceutical research.

InChI:InChI=1/C12H18N2/c1-2-9-14(10-3-1)11-6-12-4-7-13-8-5-12/h4-5,7-8H,1-3,6,9-11H2

Upstream product

• 110-89-4 piperidine 
• 100-43-6 4-vinylpyridine 

Downstream Products

• 14759-09-2 1-(2-(piperidin-4-yl)ethyl)piperidine 

Relevant articles and documents

The catalytic effect of anion-exchanged supported ionic liquid on aza-Michael-type addition

Abstract: An effective synthesis of anion-exchanged supported ionic liquids using diatomaceous earth as solid support and its catalytic effect on the aza-Michael-type addition is described. Anionic polytungstophosphate and bisulfate ion are used in the anion-exchange step in catalyst design. In addition, the aza-Michael-type addition of various amines to 2- and 4-vinyl pyridine was examined in this article. The catalytic system can be separated from the reaction mixture and recycled in subsequent reactions. The structure of anion-exchanged supported ionic liquid on diatomaceous earth was studied by XRD, FT-IR, SEM, TGA and BET techniques. The structure of organic products was determined by 1HNMR, 13CNMR, FTIR, CHN and MASS spectroscopy. Graphical Abstract: [Figure not available: see fulltext.].

Aza-Michael-type addition reaction catalysed by a supported ionic liquid phase incorporating an anionic heteropoly acid

In this work, we have obtained substituted amines under mild conditions in good yields using the Aza-Michael-type addition of various amines to vinyl compounds catalysed by a supported ionic liquid incorporating an anionic heteropoly acid. Different catalysts, including Lewis acids, Br?nsted acids and heteropoly acids were investigated in which heteropoly acids having dual Br?nsted and Lewis acid characteristics were excellent catalysts. The ionic liquid incorporating a polytungstate anion supported on magnetic diatomaceous earth as a magnetically separable heterogeneous catalyst offered the best results in terms of yield. The solid nanocatalyst was easily removed with a magnet.

Benzenesulphonamide derivatives, method for production and use thereof for treatment of pain

The present invention concerns novel benzenesulphonamide compounds, defined by formula I and the description, their method of preparation and their use in therapy.