1345203-33-9Relevant academic research and scientific papers
An enantioselective route to pyrrolidines: Removal of the chiral template from homochiral pyrroloimidazoles
Jones, Raymond C.F.,Howard, Kevin J.,Snaith, John S.,Blake, Alexander J.,Li, Wang-Shei,Steel, Peter J.
, p. 8925 - 8936 (2011)
Two-step reductive removal of the chiral template from optically active pyrroloimidazoles, available from 1,3-dipolar cycloaddition of homochiral 4,5-dihydroimidazolium ylides, gives optically active substituted pyrrolidines. Selective manipulation of the substituents affords, e.g., naturally occurring and other optically active proline derivatives, and optically active pyrrolizidines and indolizidines.
