134529-06-9Relevant articles and documents
Alkylations of (R,R)-2-t-Butyl-6-methyl-1,3-dioxan-4-ones which are not Possible with Lithium Amides may be Achieved with a Schwesinger P4 Base
Pietzonka, Thomas,Seebach, Dieter
, p. 1837 - 1843 (2007/10/02)
Enolates A of the dioxanones specified in the title, when generated with lithium amide bases, can only be alkylated with highly reactive electrophiles, and only once.With Schwesinger's t-Bu-P4 base (a very strong, so-called neutral base, containing 4P and