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Usage

Uses

Used in Organic Synthesis:
1-(3-NITROPHENYL)-2-NITROPROPENE is used as a synthetic intermediate for the production of various chemicals and materials. Its unique structure allows it to be a versatile building block in the synthesis of a wide range of compounds.
Used in Dye and Pigment Manufacturing:
1-(3-NITROPHENYL)-2-NITROPROPENE is used as a key component in the manufacture of certain dyes and pigments. Its chemical properties make it suitable for creating a variety of colors and shades in the dye and pigment industry.
Used in Pharmaceutical Research:
1-(3-NITROPHENYL)-2-NITROPROPENE is also utilized in the field of pharmaceutical research. Its potential applications in drug development and the synthesis of new pharmaceutical compounds make it a valuable compound for researchers and scientists working in the pharmaceutical industry.

InChI:InChI=1/C9H8N2O4/c1-7(10(12)13)5-8-3-2-4-9(6-8)11(14)15/h2-6H,1H3/b7-5+

Upstream product

• 79-24-3 Nitroethane 
• 99-61-6 3-nitro-benzaldehyde 
• 14439-03-3 1-(3-nitrophenyl)-2-nitro-propan-1-ol 

Downstream Products

• 1366591-26-5 3-(4-chlorophenyl)-2-methylimidazo[1,2-a]pyridine 

Relevant academic research and scientific papers

Regioselective Opening of Nitroepoxides with Unsymmetrical Diamines

Nitroepoxides are easily transformed into benzodiazepines, tetrahydrobenzodiazepines, imidazopyridines, and N-alkyl tetrahydroquinoxalines by treatment with 2-aminobenzylamines, 2-aminopyridines, and N-alkyl 1,2-diaminobenzenes, respectively. Regioselectivity is controlled through attack of the most nucleophilic nitrogen of the unsymmetrical diamine to the β position of the epoxide. These reactions represent an efficient way to prepare privileged bioactive structures.

One-pot solid phase synthesis of (E)-nitroalkenes

An efficient one-pot protocol for the synthesis of (E)-nitroalkenes by reaction of aldehydes and nitroalkanes in the presence of polymer-bound triphenylphosphine, iodine and imidazole is described. Although the reaction works with similar efficiency with triphenylphosphine and its polymer-bound version, easy removal of the unwanted polymer-bound triphenylphosphine oxide and its recovery as triphenylphosphine provide the edge for practical application of the method.

An efficient synthesis of (E)-nitroalkenes catalyzed by recoverable diamino-functionalized mesostructured polymers

A clean, efficient, and simple method has been developed for synthesis of (E)-nitroalkenes using FDU-ED as an efficient catalyst. The reactions proceeded with moderate to high yields (60-96%) under mild conditions. The catalyst FDU-ED is recyclable and can be reused more than seven times without significant loss of activity and selectivity.

Thiazole derivatives

Compounds of the formula: as well as pharmaceutically usable salts and esters thereof, wherein R1, R2and R3have the significance ascribed herein, inhibit binding of adhesive proteins to the surface of different types of cell and accordingly influence cell-cell and cell-matrix interactions. These compounds can be used in the form of pharmaceutical preparations for the control or prevention of neoplasms, tumor metastasing, tumor growth, osteoporosis, Paget's disease, diabetic retinopathy, macular degeneration, restenosis following vascular intervention, psoriasis, arthritis, fibrosis, kidney failure, as well as infection caused by viruses, bacteria or fungi.

Method and reagents for detecting amphetamine and/or d-methamphetamine in biological samples

This disclosure relates to a method and reagents for determining amphetamine and d-methamphetamine in a biological fluid, such as urine. In particular, this disclosure relates to improvements in a fluorescence polarization immunoassay procedure for determining the presence of amphetamine and d-methamphetamine in a single assay and to a novel class of tracer compounds employed as reagents in such procedures. The procedure described includes pretreatment of the biological sample to eliminate cross-reactants such as β-hydroxyphenethylamine by preincubating the sample solely with an aqueous periodate solution having a pH from about 4.0 to about 7.5 without adjustment to an alkaline pH, and contacting the sample with riboflavin binding protein to reduce interference from fluorescent components in the sample. The procedure also maintains the cross reactivity of the immunoassay for tyramine at about 0.4% and for l-methamphetamine below about 5.1% and eliminates the necessity of using controlled substances as starting materials.