1345404-99-0

Upstream product

• 930782-73-3 1-(1-benzhydrylazetidin-3-yl)piperazine 
• 1345404-98-9 6-chloro-3-ethyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 
• 1345404-97-8 4,6-dichloro-3-ethyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 
• 50424-17-4 5-amino-3-ethyl-1-phenyl-1H-pyrazole-4-carboxylic acid amide 
• 1345404-96-7 3-Ethyl-1-phenyl-1,7-dihydro-pyrazolo[3,4-d]pyrimidine-4,6-dione 

Downstream Products

• 1345404-95-6 6-(4-Azetidin-3-yl-piperazin-1-yl)-3-ethyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 

Relevant academic research and scientific papers

INDAZOLE COMPOUNDS USEFUL AS KETOHEXOKINASE INHIBITORS

The present invention is directed to substituted indazole compounds, pharmaceutical compositions of these compounds and methods of use thereof. The compounds of the present invention are ketohexokinase (KHK) inhibitors, useful for treating or ameliorating a KHK mediated metabolic disorders and/or diseases such as obesity, Type II diabetes mellitus and Metabolic Syndrome X.