1345512-27-7

Basic information

• Product Name: 3-chloro-N-(3-mercapto-5-(naphthalen-1-yl)-4H-1,2,4-triazol-4-yl)benzamide
• CAS NO: 1345512-27-7
• Molecular Weight: 380.857
• Mol File: 1345512-27-7.mol

Chemical Properties

• CAS DataBase Reference: 3-chloro-N-(3-mercapto-5-(naphthalen-1-yl)-4H-1,2,4-triazol-4-yl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-N-(3-mercapto-5-(naphthalen-1-yl)-4H-1,2,4-triazol-4-yl)benzamide(1345512-27-7)
• EPA Substance Registry System: 3-chloro-N-(3-mercapto-5-(naphthalen-1-yl)-4H-1,2,4-triazol-4-yl)benzamide(1345512-27-7)

Safety Data

• Hazardous Substances Data: 1345512-27-7(Hazardous Substances Data)

Upstream product

• 1673-47-8 3-chlorobenzhydrazide 

Relevant articles and documents

Synthesis, characterization, and antimicrobial evaluation of novel naphthalene-based 1,2,4-triazoles

In order to search for new bioactive molecules with significant antimicrobial action, a series of 1,2,4-triazole and naphthalene analogs bearing structurally diverse substituents, N-(3-mercapto-5-(naphthalen-1-yl)-4H-1,2,4- triazol-4-yl)(aryl)amides 3a-l were synthesized in good yield by a multi-step synthetic procedure. Their antimicrobial activity was screened against various Gram-positive and Gram-negative bacteria and fungi. Compounds 3a, 3f, 3g, 3j, and 3k exerted strong inhibition of the investigated bacterial and fungal strains compared to control antibiotic ampicillin and antifungal griseofulvin. On the basis of statistical analysis, it is observed that the compounds give significant co-relation. All the synthesized compounds have been characterized by IR, 1H NMR, 13C NMR, and mass spectral data. Springer Science+Business Media, LLC 2011.