1345622-75-4Relevant academic research and scientific papers
Iodobenzene catalysed synthesis of spirofurans and benzopyrans by oxidative cyclisation of vinylogous esters
Ngatimin, Marsewi,Frey, Raphael,Andrews, Cecily,Lupton, David W.,Hutt, Oliver E.
, p. 11778 - 11780 (2011/12/15)
Vinylogous esters bearing para or meta methoxy benzyl groups undergo oxidative cyclisation with 5-20 mol% iodobenzene and m-CPBA to give spirofuran or benzopyran containing heterocycles. The reaction allows rapid generation of skeletal complexity in good to excellent yields via a novel oxidative cyclisation.
