134566-65-7

Basic information

• Product Name: 1-{[2-(dimethylamino)ethyl]amino}-5,8-dihydroxy-4-({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione
• Synonyms: 1-((2-(Dimethylamino)ethyl)amino)-4-((2-((2-hydroxyethyl)amino)ethyl)amino)-5,8-dihydroxyanthracene-9,10-dione; 9,10-Anthracenedione, 1-((2-(dimethylamino)ethyl)amino)-5,8-dihydroxy-4-((2-((2-hydroxyethyl)amino)ethyl)amino)-; 9,10-anthracenedione, 1-[[2-(dimethylamino)ethyl]amino]-5,8-dihydroxy-4-[[2-[(2-hydroxyethyl)amino]ethyl]amino]-
• CAS NO: 134566-65-7
• Molecular Formula: C₂₂H₂₈N₄O₅
• Molecular Weight: 428.4815
• Mol File: 134566-65-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 738.5°C at 760 mmHg
• Flash Point: 400.4°C
• Density: 1.393g/cm³
• Vapor Pressure: 6.72E-23mmHg at 25°C
• Refractive Index: 1.695
• CAS DataBase Reference: 1-{[2-(dimethylamino)ethyl]amino}-5,8-dihydroxy-4-({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{[2-(dimethylamino)ethyl]amino}-5,8-dihydroxy-4-({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione(134566-65-7)
• EPA Substance Registry System: 1-{[2-(dimethylamino)ethyl]amino}-5,8-dihydroxy-4-({2-[(2-hydroxyethyl)amino]ethyl}amino)anthracene-9,10-dione(134566-65-7)

Safety Data

• Hazardous Substances Data: 134566-65-7(Hazardous Substances Data)

Upstream product

• 29559-82-8 N'-ethyl-N,N-dimethyl-hydrazine 
• 23478-60-6 leuco-1,4,5,8-tetrahydroxyanthraquinone 
• 131401-54-2 1,4-Difluoro-5,8-dihydroxyanthracene-9,10-dione 
• 134529-37-6 1-<<2-(dimethylamino)ethyl>amino>-4-fluoro-5,8-dihydroxyanthracene-9,10-dione 

Relevant articles and documents

Anti-cancer compounds

Compounds of formula (I) STR1 in which R1, R2, R3 and R4 are each separately selected from hydrogen, X, NH--A--NHR and NH--A--N(O)R'R" wherein X is hydroxy, halogeno, amino, C1-4 alkoxy or C2-8 alkanoyloxy, A is a C2-4 alkylene group with a chain length between NH and NHR or N(O)R'R" of at least 2 carbon atoms and R, R' and R" are each separately selected from C1-4 alkyl groups and C2-4 hydroxyalkyl and C2-4 dihydroxyalkyl groups in which the carbon atom attached to the nitrogen atom does not carry a hydroxy group and no carbon atom is substituted by two hydroxy groups, or R' and R" together are a C2-6 alkylene group which with the nitrogen atom to which R" and R" are attached forms a heterocyclic group having 3 to 7 atoms in the ring, but with the proviso that at least one of R1 to R4 is a group NH--A--N(O)R'R", and physiologically acceptable salts thereof are of value in the treatment of cancer.