1345683-00-2

Upstream product

• 626-61-9 4-Chloropyridine 
• 1345683-11-5 (4-chloropyridin-3-yl)(3,4-dimethoxyphenyl)methanol 
• 1345682-92-9 (4-chloropyridin-3-yl)(3,4-dimethoxyphenyl)methanone 
• 1345682-96-3 (3,4-dimethoxyphenyl)[4-(ethylsulfanyl)pyridin-3-yl]methanone 
• 19493-09-5 Methylenetriphenylphosphorane 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Downstream Products

• 1345683-04-6 3-[1-(3,4-dimethoxyphenyl)ethenyl]-4-(ethylsulfinyl)pyridine 
• 1345682-76-9 3-(3,4-dimethoxyphenyl)thieno[3,2-c]pyridine 

Relevant academic research and scientific papers

Synthesis of 3-arylthieno[2,3-b]-, -[2,3-c]- or -[3,2-c]pyridines utilizing an interrupted pummerer reaction

An efficient procedure for the synthesis of three types of thienopyridines has been developed. Thus, 3-(1-arylethenyl)-2-(ethylsulfinyl)pyridines, 4-(1-arylethenyl)-3-(ethylsulfinyl)pyridines, and 3-(1-arylethenyl)-4- (ethylsulfinyl)pyridines, which can be easily prepared from the respective aryl chloropyridinyl ketones in a three-step sequence, undergo an interrupted Pummerer reaction on treatment with excess acetic anhydride at temperatures ranging from 100 to 130 C to give 3-arylthieno[2,3-b]pyridines, 3-aryl-thieno[2,3-c]pyridines, and 3-arylthieno[3,2-c]pyridines, respectively. Georg Thieme Verlag Stuttgart - New York.