13457-18-6

Basic information

• Product Name: PYRAZOPHOS
• Synonyms: AFUGAN;Afugan powder;AFUGAN(R);ETHYL-2-DIETHOXYPHOSPHINOTHIOYLOXY-5-METHYLPYRAZOLO[1,5-A]-PYRIMIDINE-6-CARBOXYLATE;PYRAZOPHOS;Pyrazophos emulsion(content>15%);Pyrazophos powder(content>55%);O,O-DIETHYL-O-6-ETHOXYCARBONYL-5-METHYL-PYRAZOLO [1,5-A]PYRIMIDIN-2-YL-PHOSPHOROTHIONATE
• CAS NO: 13457-18-6
• Molecular Formula: C₁₄H₂₀N₃O₅PS
• Molecular Weight: 373.36
• EINECS: 236-656-1
• Product Categories: OrganophosphorusAlphabetic;Fungicides;P;Pesticides;PU - PZ;Alpha sort;N-PPesticides;Pesticides&Metabolites
• Mol File: 13457-18-6.mol
• Article Data: 10

Chemical Properties

• Melting Point: 51℃
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.38g/cm³
• Vapor Pressure: 2.2 x 10-4 Pa (50 °C)
• Refractive Index: 1.595
• Storage Temp.: APPROX 4°C
• PKA: -1.37±0.40(Predicted)
• Water Solubility: 4.2 mg l-1 (25 °C)
• Merck: 13,8052
• BRN: 577209
• CAS DataBase Reference: PYRAZOPHOS(CAS DataBase Reference)
• NIST Chemistry Reference: PYRAZOPHOS(13457-18-6)
• EPA Substance Registry System: PYRAZOPHOS(13457-18-6)

Safety Data

• Hazard Codes: Xn,N
• Statements: 20/22-50/53
• Safety Statements: 36/37-46-60-61
• RIDADR: 2783
• WGK Germany: 3
• RTECS: TF2035000
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 13457-18-6(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 13457-18-6 differently. You can refer to the following data:
1. Fungicide.
2. Pyrazophos is a systemic fungicide that provides both protective and curative control of various fungal diseases such as powdery mildew (Podosphaera) on apples, stone fruits, bush fruits and strawberries, Erysiphe in cucurbits and tomatoes, Uncinula on vines and leaf blotch (Rhynchosporium) in cereals.
3. Pyrazophos is an anticholinesterase pesticide used on fruits and vegetables and can be determined by gas chromatography/mass spectrometry and liquid chromatography with fluorescence detection.

Definition

ChEBI: A member of the class of pyrazolopyrimidines that is the ethyl ester of 2-[(diethoxyphosphorothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid. A fungicide used to control Erysiphe, Helminthosporium and ital>Rhynchospium in cereals.

Metabolic pathway

Limited information is available to describe the degradation and metabolic fate of pyrazophos. Hydrolytic cleavage of the P-O-pyrazolopyrimidine linkage is the primary metabolic pathway. Oxidative desulfuration of pyrazophos to pyrazophos-oxon is only a minor pathway, observed in the plant metabolism study (Scheme 1).

Metabolism

Its mode of action is believed to be the inhibition of melanin biosynthesis and the development of appressoria by fungal conidia. Formulation is available as emulsifiable concentrate (EC: 30%). Application rates on Oidium spp. are in the range of 15–30 g a.i./hl.

Degradation

Pyrazophos (1) is hydrolysed in acidic or alkaline solution (PM).

InChI:InChI=1/C14H20N3O5PS/c1-5-19-14(18)11-9-17-12(15-10(11)4)8-13(16-17)22-23(24,20-6-2)21-7-3/h8-9H,5-7H2,1-4H3

Relevant articles and documents

Substituted imide derivatives

The present invention relates to novel substituted imide derivatives of the general formula (I) in which R1 represents optionally substituted cycloalkyl, R2 represents optionally substituted alkyl or optionally substituted cycloalkyl, R3 represents alkyl, alkoxy, alkylthio, amino, alkylamino or dialkylamino and R4 represents cyano or nitro, and to processes for their preparation and to their use for controlling animal pests and as herbicides.

Composition for controlling harmful bio-organisms and method for controlling harmful bio-organisms using the same

A composition for controlling harmful bio-organisms comprising (a) at least one imidazole compound represented by formula (I): wherein R represents a lower alkyl group or a lower alkoxy group; and n represents an integer of 1 to 5, as an active ingredient, and (b) at least one inorganic phosphorus compound and/or at least one fungicide for Phycomycetes as an active ingredient or (c) a spreader as an activity-enhancing ingredient, and a method for controlling harmful bio-organisms comprising applying the composition for controlling harmful bio-organisms onto harmful bio-organisms.

Iminoacetic acid amides and their use as pest control agents

PCT No. PCT/EP96/04345 Sec. 371 Date Apr. 15, 1998 Sec. 102(e) Date Apr. 15, 1998 PCT Filed Oct. 7, 1996 PCT Pub. No. WO97/14673 PCT Pub. Date Apr. 24, 1997Iminoacetamides of the formula (I) in which A represents a single bond or optionally substituted alkylene, Q represents oxygen or sulphur, R1 represents respectively optionally substituted cycloalkyl, cycloalkenyl, aryl or heterocyclyl, R2 represents respectively optionally substituted alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkenyl, aryl or heterocyclyl, R3 represents hydrogen or respectively optionally substituted alkyl, alkenyl, alkinyl or cycloalkyl, R4 represents respectively optionally substituted cycloalkyl, cycloalkenyl, aryl or heterocyclcyl a process for their preparation, pesticidal compositions containing them, and their use for controlling pests.