1345824-17-0

Basic information

• Product Name: (S)-N,N'-(1-(4-((1,3-dioxoisoindolin-2-yl)methyl)phenyl)ethane-1,2-diyl)bis(N-(methylsulfonyl)methanesulfonamide)
• Synonyms: (S)-N,N'-(1-(4-((1,3-dioxoisoindolin-2-yl)methyl)phenyl)ethane-1,2-diyl)bis(N-(methylsulfonyl)methanesulfonamide)
• CAS NO: 1345824-17-0
• Molecular Weight: 607.708
• Mol File: 1345824-17-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (S)-N,N'-(1-(4-((1,3-dioxoisoindolin-2-yl)methyl)phenyl)ethane-1,2-diyl)bis(N-(methylsulfonyl)methanesulfonamide)(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N,N'-(1-(4-((1,3-dioxoisoindolin-2-yl)methyl)phenyl)ethane-1,2-diyl)bis(N-(methylsulfonyl)methanesulfonamide)(1345824-17-0)
• EPA Substance Registry System: (S)-N,N'-(1-(4-((1,3-dioxoisoindolin-2-yl)methyl)phenyl)ethane-1,2-diyl)bis(N-(methylsulfonyl)methanesulfonamide)(1345824-17-0)

Safety Data

• Hazardous Substances Data: 1345824-17-0(Hazardous Substances Data)

Upstream product

• 63413-74-1 2-(4-ethenylbenzyl)-1H-isoindole-1,3(2H)-dione 
• 5347-82-0 dimesylamine 

Relevant articles and documents

Catalytic Asymmetric Diamination of Styrenes

An enantioselective catalytic vicinal diamination of styrenes is reported, which proceeds under entirely intermolecular reaction control. It relies on a chirally modified aryliodine(I) catalyst and proceeds within an iodine(I/III) manifold with conventional 3-chloroperbenzoic acid as a terminal oxidant. An environmentally benign solvent combination not only adds to the attractiveness of the process but also slows down the rate of the undesired background reaction. A total of 30 examples are presented, which consistently provide high enantiomeric excesses in the range 91-98%.

Enantioselective metal-free diamination of styrenes

Metal-free and asymmetric: The first enantioselective diamination of styrenes simply requires a chiral hypervalent iodine(III) reagent as an oxidant and bismesylimide as a nitrogen source (see scheme, Ms=methanesulfonyl). The reaction proceeds under mild conditions and with high enantiomeric excess.