1345841-49-7Relevant academic research and scientific papers
Design, synthesis, and biological activity of a novel series of 2,5-disubstituted furans/pyrroles as HIV-1 fusion inhibitors targeting gp41
Jiang, Shibo,Tala, Srinivasa R.,Lu, Hong,Zou, Peng,Avan, Ilker,Ibrahim, Tarek S.,Abo-Dya, Nader E.,Abdelmajeid, Abdelmotaal,Debnath, Asim K.,Katritzky, Alan R.
, p. 6895 - 6898 (2011/12/22)
Based on molecular docking analysis of earlier results, we designed a series of 2,5-disubstituted furans/pyrroles (5a-h) as HIV-1 entry inhibitors. Compounds were synthesized by Suzuki-Miyaura cross coupling, followed by a Knoevenagel condensation or Witt
