1345876-72-3

Basic information

• Product Name: (1R,2R)-methyl 2-(3,4-dichlorophenyl)-1-((E)-styryl)cyclopropanecarboxylate
• Synonyms: (1R,2R)-methyl 2-(3,4-dichlorophenyl)-1-((E)-styryl)cyclopropanecarboxylate
• CAS NO: 1345876-72-3
• Molecular Weight: 347.241
• Mol File: 1345876-72-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (1R,2R)-methyl 2-(3,4-dichlorophenyl)-1-((E)-styryl)cyclopropanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,2R)-methyl 2-(3,4-dichlorophenyl)-1-((E)-styryl)cyclopropanecarboxylate(1345876-72-3)
• EPA Substance Registry System: (1R,2R)-methyl 2-(3,4-dichlorophenyl)-1-((E)-styryl)cyclopropanecarboxylate(1345876-72-3)

Safety Data

• Hazardous Substances Data: 1345876-72-3(Hazardous Substances Data)

Upstream product

• 2039-83-0 3,4-dichlorostyrene 
• 119987-21-2 (E)-methyl 2-diazo-4-phenylbut-3-enoate 

Relevant articles and documents

D 2-symmetric dirhodium catalyst derived from a 1,2,2-triarylcyclopropanecarboxylate ligand: Design, synthesis and application

Dirhodium tetrakis-(R)-(1-(4-bromophenyl)-2,2- diphenylcyclopropanecarboxylate) (Rh2(R-BTPCP)4) was found to be an effective chiral catalyst for enantioselective reactions of aryl- and styryldiazoacetates. Highly enantioselective cyclopropanations, tandem cyclopropanation/Cope rearrangements and a combined C-H functionalization/Cope rearrangement were achieved using Rh2(R-BTPCP)4 as catalyst. The advantages of Rh2(R-BTPCP)4 include its ease of synthesis, its tolerance to the size of the ester group in the styryldiazoacetates, and its compatibility with dichloromethane as solvent. Computational studies suggest that the catalyst adopts a D2-symmetric arrangement, but when the carbenoid binds to the catalyst, two of the p-bromophenyl groups on the ligands rotate outward to make room for the carbenoid and the approach of the substrate to the carbenoid.