13459-59-1

Usage

Uses

Used in Pharmaceutical Industry:
(2-[(4-Chlorophenyl)sulfanyl]phenyl)methanol is used as a key intermediate in the synthesis of drugs, leveraging its antimicrobial and anti-inflammatory properties to contribute to the development of therapeutic agents.
Used in Agricultural Industry:
(2-[(4-Chlorophenyl)sulfanyl]phenyl)methanol is used as a potential fungicide and insecticide, owing to its ability to combat microbial and insect pests, thereby enhancing crop protection and yield.

InChI:InChI=1/C13H11ClOS/c14-11-5-7-12(8-6-11)16-13-4-2-1-3-10(13)9-15/h1-8,15H,9H2

Upstream product

• 5159-41-1 2-iodobenzyl alcohol 
• 106-54-7 p-Chlorothiophenol 
• 107572-07-6 2-[(4-chlorophenyl)thio]benzaldehyde 
• 6469-86-9 2-<4-Chlor-phenylthio>-benzoesaeurechlorid 
• 41932-35-8 1-[2-(4-chloro-phenylsulfanyl)-phenyl]-ethanone 
• 41932-36-9 4-{[2-(4-chloro-phenylsulfanyl)-phenyl]-oxo-thioacetyl}-morpholine 
• 6469-85-8 2-carboxyphenyl 4-chlorophenyl sulphide 

Downstream Products

• 1181080-16-9 4-{3-[2-(4-chlorobenzenesulfinyl)benzyl]-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl}-2-trifluoromethylbenzonitrile 
• 1181080-15-8 4-{3-[2-(4-Chlorobenzenesulfonyl)benzyl]-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl}-2-trifluoromethylbenzonitrile 
• 41932-37-0 2-(4-chlorophenylsulfanyl)benzyl bromide 
• 1181080-14-7 4-{3-[2-(4-Chlorophenylsulfanyl)benzyl]-4,4-dimethyl-2,5-dioxoimidazolidin-1-yl}-2-trifluoromethylbenzonitrile 

Relevant academic research and scientific papers

Manganese-catalyzed cross-coupling of thiols with aryl iodides

A manganese-catalyzed cross-coupling reaction of thiols with aryl iodides, furnishing aryl thioethers in good to excellent yields has been reported; the system shows good functional group tolerance and enables the sterically demanding aryl iodides to couple with thiols. Coming up for ArI: A manganese-catalyzed cross-coupling reaction of thiols with aryl iodides that furnishes aryl thioethers in good to excellent yields has been reported. Functional groups such as unprotected alcohols and chloro substituents are tolerated under these reaction conditions. Moreover, this catalytic system enables the sterically demanding aryl iodides to couple with thiols (see scheme; R=aryl or alkyl).

Ionene-bound borohydrides: Efficient, selective, and versatile polymer-supported reducing agents

Reduction of structurally different carbonyl compounds, such as aldehydes, ketones, α,β-unsaturated enals and enones, acid chlorides, and imines was accomplished efficiently using high capacity ionene based borohydride reagents. Aldehydes and imines were reduced to the corresponding alcohols and amines in excellent yields in methanol at ambient temperature while ketones and acid chlorides were reduced in iso-propanol and THF-MeOH at reflux. Chemoselective reduction of aldehydes over ketones was achieved successfully with these reagents. Complete regioselectivity was also observed in the reduction of α,β-unsaturated aldehydes and ketones.