1345992-93-9Relevant academic research and scientific papers
Synthesis and biological evaluation of acyclic phosphonic acid nucleoside derivatives
Wainwright, Philip,Maddaford, Adrian,Zhang, Xiurong,Billington, Helen,Leese, David,Glen, Rebecca,Pryde, David C.,Middleton, Donald S.,Stephenson, Peter T.,Sutton, Scott
, p. 477 - 492 (2013/10/22)
As part of a project to generate a library of nucleosides as potential antiviral agents, a small subset of novel acyclic phosphonic acid nucleosides was prepared. Practical synthetic routes are described for three targets, which were then tested against H
Practical synthetic routes to carbon-substituted nucleosides
Pryde, David C.,Middleton, Donald S.,Stephenson, Peter T.,Wainwright, Philip,Maddaford, Adrian,Zhang, Xiurong,Leese, David,Glen, Rebecca,Hart, James,Forrest, Neil,Guyot, Thierry
, p. 6415 - 6419 (2011/12/21)
Robust practical routes to three different carbon-substituted nucleosides are described. Short synthetic procedures for preparing 1-homonucleosides, 2'-C-methyl-carbanucleosides and 2'-C-methyl-cyclopro-pyl/cyclopentyl fused bicyclic ribose analogues are described starting from readily available building blocks. Crown Copyright
