134604-07-2Relevant articles and documents
Method for preparing 3,5-disubstituted oxadiazole compound
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Paragraph 0024; 0029-0030, (2019/04/30)
The invention discloses a method for preparing a 3,5-disubstituted oxadiazole compound N-((3-(2-bromo-5-nitrophenyl)-1,2,4-oxadiazole-5-yl)methyl)ethylamine. 4-nitrobromobenzene used as a starting material undergoes hydroformylation, oximation, eliminatio
Aromatic allylation via diazotization: Metal-free C-C bond formation
Ek, Fredrik,Axelsson, Oskar,Wistrand, Lars-Goeran,Frejd, Torbjoern
, p. 6376 - 6381 (2007/10/03)
A new method for the synthesis of allyl aromatic compounds not involving any metal-containing reagent or catalyst has been developed. Arylamines substituted with a large number of different substituents were converted via diazotizative deamination with tert-butyl nitrite in allyl bromide and acetonitrile to the corresponding allyl aromatic compounds. The allylation reaction was found to be suitable for larger scale synthesis due to short reaction times, a nonextractive workup, and robustness toward moisture, air, and type of solvent.