134610-30-3

Basic information

• Product Name: Benzoyl chloride, 3,4-dimethoxy-5-nitro-
• Synonyms: 3,4-dimethoxy-5-nitrobenzoylchloride;3,4-Dimethoxy-5-nitro-benzoyl chloride
• CAS NO: 134610-30-3
• Molecular Formula: C9H8ClNO5
• Molecular Weight: 245.619
• Mol File: 134610-30-3.mol

Chemical Properties

• Melting Point: 68 - 70 °C
• CAS DataBase Reference: Benzoyl chloride, 3,4-dimethoxy-5-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 3,4-dimethoxy-5-nitro-(134610-30-3)
• EPA Substance Registry System: Benzoyl chloride, 3,4-dimethoxy-5-nitro-(134610-30-3)

Safety Data

• Hazardous Substances Data: 134610-30-3(Hazardous Substances Data)

Upstream product

• 121-33-5 vanillin 
• 22027-96-9 5-nitroveratral 
• 6635-20-7 isonitrovanillin 

Downstream Products

• 134610-31-4 diethyl 3,4-dimethoxy-5-nitrobenzoylmalonate 
• 866109-47-9 N-(5-phthalimidopentyl)-3,4-dimethoxy-5-nitrobenzamide 
• 866109-50-4 N-[5-(4-methoxybenzoylamino)pentyl]-3,4-dimethoxy-5-nitrobenzamide 
• 866109-45-7 N-(4-phthalimidobutyl)-3,4-dimethoxy-5-nitrobenzamide 
• 866109-49-1 N-[4-(4-methoxybenzoylamino)butyl]-3,4-dimethoxy-5-nitrobenzamide 
• 866109-43-5 5-(3,4-dimethoxy-5-nitrobenzamido)pentan-1-ol p-toluenesulfonin acid ester 
• 866109-41-3 4-(3,4-dimethoxy-5-nitrobenzamido)butan-1-ol p-toluenesulfonic acid ester 
• 866109-38-8 N-[3-(4-methoxybenzoylamino)propyl]-3,4-dimethoxy-5-nitrobenzamide 
• 866109-51-5 N-methyl-(3,4-dimethoxy-5-nitrobenzamide) 
• 866109-35-5 N,N'-1,4-butanediylbis(3,4-dimethoxy-5-nitrobenzamide) 
• 866109-34-4 N,N'-1,3-propanediylbis(3,4-dimethoxy-5-nitrobenzamide) 

Relevant articles and documents

Synthesis and evaluation of bifunctional nitrocatechol inhibitors of pig liver catechol-O-methyltransferase

Bifunctional compounds were tested in vitro as potential inhibitors of pig liver catechol-O-methyltransferase (COMT) with respect to the catechol substrate 4-[(3,4-dihydroxyphenyl)azo]benzenesulfonate. The bifunctional compounds were a composite of either two nitrocatechols or one nitrocatechol and one phenol, linked by amide bonds to a spacer unit comprising two to five methylene groups. The unsymmetrical compounds N-[2-(4-hydroxybenzoylamine)ethyl]-3,4-dihydroxy-5- nitrobenzamide], N-[3-(4-hydroxybenzoyl-amine)propyl]-3,4-dihydroxy-5- nitrobenzamide] and N-[5-(4-hydroxybenzoylamine)pentyl]-3,4-dihydroxy-5- nitrobenzamide] demonstrated strong inhibitory action against COMT with K i values in the 100 nM range. In comparison, the monofunctional nitrocatechol analogues of these compounds had Ki values that were significantly higher.