1346136-03-5

Basic information

• Product Name: methyl 4-(2-{4-[(cyanoacetyl)amino]phenyl}ethyl)benzoate
• Synonyms: methyl 4-(2-{4-[(cyanoacetyl)amino]phenyl}ethyl)benzoate
• CAS NO: 1346136-03-5
• Molecular Weight: 322.364
• Mol File: 1346136-03-5.mol

Chemical Properties

• CAS DataBase Reference: methyl 4-(2-{4-[(cyanoacetyl)amino]phenyl}ethyl)benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 4-(2-{4-[(cyanoacetyl)amino]phenyl}ethyl)benzoate(1346136-03-5)
• EPA Substance Registry System: methyl 4-(2-{4-[(cyanoacetyl)amino]phenyl}ethyl)benzoate(1346136-03-5)

Safety Data

• Hazardous Substances Data: 1346136-03-5(Hazardous Substances Data)

Upstream product

• 1346136-01-3 methyl 4-[2-(4-aminophenyl)ethyl]benzoate 
• 372-09-8 cyanoacetic acid 
• 136827-59-3 methyl 4-[(E)-2-(4-nitrophenyl)ethenyl]benzoate 
• 1571-08-0 methyl 4-formylbenzoate 
• 2609-49-6 diethyl p-nitrobenzylphosphonate 

Downstream Products

• 1346134-71-1 methyl 4-[2-(4-{[(2-{[3-(cyclopropylsulfamoyl)benzoyl]amino}-4,5,6,7-tetrahydro-1-benzothiophen-3-yl)carbonyl]amino}phenyl)ethyl]benzoate 
• 1346134-72-2 methyl 4-{2-[4-({[2-({3-[(4-ethoxy-4-oxobutyl)sulfamoyl]benzoyl}amino)-4,5,6,7-tetrahydro-1-benzothiophen-3-yl]carbonyl}amino)phenyl]ethyl}benzoate 
• 1346134-46-0 methyl 4-{2-[4-({[2-({3-[(3-tert-butoxy-3-oxopropyl)(methyl)sulfamoyl]benzoyl}amino)-4,5,6,7-tetrahydro-1-benzothiophen-3-yl]carbonyl}amino)phenyl]ethyl}benzoate 
• 1346134-47-1 4-{2-[4-({[2-({3-[(2-carboxyethyl)(methyl)sulfamoyl]benzoyl}amino)-4,5,6,7-tetrahydro-1-benzothiophen-3-yl]carbonyl}amino)phenyl]ethyl}benzoic acid 
• 1346134-48-2 methyl 4-{2-[4-({[2-({3-[cyclopropyl(4-ethoxy-4-oxobutyl)sulfamoyl]benzoyl}amino)-4,5,6,7-tetrahydro-1-benzothiophen-3-yl]carbonyl}amino)phenyl]ethyl}benzoate 
• 1346136-57-9 methyl 4-(2-{4-[({2-[(3-{[1-(ethoxycarbonyl)cyclopropyl]sulfamoyl}benzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophen-3-yl}carbonyl)amino]phenyl}ethyl)benzoate 
• 1346134-50-6 methyl 4-(2-{4-[({2-[(3-{[1-(ethoxycarbonyl)cyclopropyl](ethyl)sulfamoyl}benzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophen-3-yl}carbonyl)amino]phenyl}ethyl)benzoate 
• 1346134-51-7 4-{2-[4-({[2-({3-[(1-carboxycyclopropyl)(ethyl)sulfamoyl]benzoyl}amino)-4,5,6,7-tetrahydro-1-benzothiophen-3-yl]carbonyl}amino)phenyl]ethyl}benzoic acid 
• 1346134-52-8 methyl 4-(2-{4-[({2-[(3-{[1-(ethoxycarbonyl)cyclopropyl](isopropyl)sulfamoyl}benzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophen-3-yl}carbonyl)amino]phenyl}ethyl)benzoate 
• 1346134-53-9 4-(2-{4-[({2-[(3-{[1-(ethoxycarbonyl)cyclopropyl](isopropyl)sulfamoyl}benzoyl)amino]-4,5,6,7-tetrahydro-1-benzothiophen-3-yl}carbonyl)amino]phenyl}ethyl)benzoic acid 
• 1346134-54-0 4-{2-[4-({[2-({3-[(1-carboxycyclopropyl)(isopropyl)sulfamoyl]benzoyl}amino)-4,5,6,7-tetrahydro-1-benzothiophen-3-yl]carbonyl}amino)phenyl]ethyl}benzoic acid 
• 1346134-55-1 methyl 6-[{[3-({3-[(4-{2-[4-(methoxycarbonyl)phenyl]ethyl}phenyl)carbamoyl]-4,5,6,7-tetrahydro-1-benzothiophen-2-yl}carbamoyl)phenyl]sulfonyl}(propyl)amino]nicotinate 
• 1346136-60-4 methyl 4-({[3-({3-[(4-{2-[4-(methoxycarbonyl)phenyl]ethyl}phenyl)carbamoyl]-4,5,6,7-tetrahydro-1-benzothiophen-2-yl}carbamoyl)phenyl]sulfonyl}amino)benzoate 
• 1346134-57-3 methyl 4-(ethyl{[3-({3-[(4-{2-[4-(methoxycarbonyl)phenyl]ethyl}phenyl)carbamoyl]-4,5,6,7-tetrahydro-1-benzothiophen-2-yl}carbamoyl)phenyl]sulfonyl}amino)benzoate 

Relevant articles and documents

Thiophene compound Tetrahydrobenza and (by machine translation)

The purpose of this invention is to provide with intestinal phosphate transport protein inhibit function (NPT-IIb), hyperphosphatemia as a therapeutic and/or preventive agent for Tetrahydrobenza the effective ingredient of benzothiophene compound or its stereoisomers, geometric isomers, tautomers, nitrogen oxide, hydrate, solvate, metabolite, ester, pharmaceutically acceptable salt or its prodrug and pharmaceutical composition. (by machine translation)

AMINOALKYL-SUBSTITUTED N-THIENYL BENZAMIDE DERIVATIVE

[Problem] To provide a compound that has an intestinal phosphate transporter (NPT-IIb) inhibitory action and is useful as an active ingredient of an agent for treating and/or preventing hyperphosphatemia. [Means for Solution] The present inventors conduct

TETRAHYDROBENZOTHIOPHENE COMPOUND

The purpose is to provide a compound which has an intestinal phosphate transporter (NPT-IIb) inhibitory action and is useful as an active ingredient of an agent for treating and/or preventing hyperphosphatemia. A tetrahydrobenzothiophene compound of the following formula (I) has NPT-IIb inhibitory action and can be used as an agent for treating and/or preventing hyperphosphatemia: wherein, R1 represents -O-lower alkyl, -lower alkylene-phenyl, or the like; R2 and R3 are the same as or different from each other and represent H, lower alkyl, cycloalkyl, aryl, heteroaryl or the like, or, R2 and R3 may be combined with a nitrogen atom to which they bind to form 5- to 7-membered saturated cyclic amino; R4,s are the same as or different from each other and represent halogen, lower alkyl; and n represents 0 to 2.