1346169-75-2Relevant academic research and scientific papers
Application of Suzuki arylation, Sonogashira ethynylation and Rosenmund-von Braun cyanation in the exploration of substitution effects on the anticancer activity of 2-aroylquinolines
Lee, Hsueh-Yun,Lee, Lin-Wen,Nien, Chih-Ying,Kuo, Ching-Chuan,Lin, Pen-Yuan,Chang, Chi-Yen,Chang, Jang-Yang,Liou, Jing-Ping
, p. 9593 - 9600 (2013/01/16)
A variety of functionalities were introduced at 2-aroylquinoline's C5 position, which is considered equivalent to C-3′ of the B-ring of CA4, via Suzuki arylation, Sonogashira ethynylation, and Rosenmund-von Braun cyanation. These substitutions are rarely
AROYLQUINOLINE COMPOUNDS
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, (2011/11/13)
A serious of nitro heterocyclic derivatives including a structure of formula (I) are provided. In formula (I), P, Q and R1 to R8 are defined in the specification. The derivatives disclosed in the present invention are characterized in inhibiting tubulin p
