1346169-91-2Relevant academic research and scientific papers
5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2
Lee, Hsueh-Yun,Chang, Jang-Yang,Nien, Chih-Ying,Kuo, Ching-Chuan,Shih, Kuang-Hsing,Wu, Chun-Hsein,Chang, Chi-Yen,Lai, Wen-Yang,Liou, Jing-Ping
, p. 8517 - 8525 (2012/02/03)
A variety of studies on the modification of combretastatin A-4 triggered our interest in the impact of the linkers between the 3,4,5-trimethoxyphenyl ring and 5-amino-6-methoxyquinoline on biological activity. The replacement of the carbonyl group with bo
AROYLQUINOLINE COMPOUNDS
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Page/Page column 15, (2011/11/13)
A serious of nitro heterocyclic derivatives including a structure of formula (I) are provided. In formula (I), P, Q and R1 to R8 are defined in the specification. The derivatives disclosed in the present invention are characterized in inhibiting tubulin p
