134622-65-4

Basic information

• Product Name: 3-(benzylamino)-2-methylcyclopent-2-en-1-one
• Synonyms: 3-(benzylamino)-2-methylcyclopent-2-en-1-one
• CAS NO: 134622-65-4
• Molecular Weight: 201.268
• Mol File: 134622-65-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3-(benzylamino)-2-methylcyclopent-2-en-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(benzylamino)-2-methylcyclopent-2-en-1-one(134622-65-4)
• EPA Substance Registry System: 3-(benzylamino)-2-methylcyclopent-2-en-1-one(134622-65-4)

Safety Data

• Hazardous Substances Data: 134622-65-4(Hazardous Substances Data)

Upstream product

• 765-69-5 2-Methylcyclopentane-1,3-dione 
• 100-46-9 benzylamine 
• 5870-63-3 3-hydroxy-2-methyl-2-cyclopenten-1-one 

Downstream Products

• 152496-58-7 N-benzyl,N-(2-methyl-3-oxo-cyclopent-1-enyl)-2-methoxyacetamide 
• 183674-23-9 N-benzyl-N-(2-methyl-3-oxocyclopent-1-enyl)pent-4-enamide 
• 175469-20-2 N-benzyl,N-(3-oxo-cyclopent-1-enyl)-2-diallylaminoacetamide 

Relevant articles and documents

Photorearrangement of N-alkanoyl β-enaminones. Application to the synthesis of α-amino-β,γ-unsaturated acid derivatives

The irradiation of N-alkanoyll-β-enaminones lead to the formation of spiranic β-lactams which undergo C-N bond cleavage during chromatography on alumina giving cycloalkenones functionalized at position 3. This new rearrangement has been applied to the synthesis of α-amino-β,γ-unsaturated amides in one step and gives convenient yields.

Synthesis of N-substituted 2-alkyl-3-amino-3-cyclopenten-1-ones

Several 2-alkyl-3-amino-2-cyclopenten-1-ones are prepared in 45-92% yield from 2-alkyl-1,3-cyclopentanediones and a slight excess of an equimolar mixture of various primary and secondary amines and acetic or propionic acid in boiling toluene.