1346233-68-8

Basic information

• Product Name: 3,5-Dichloro-N-[[(1α,5α,6-exo,6α)-3-(3,3-diMethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]Methyl]-benzaMide
• Synonyms: 3,5-Dichloro-N-[[(1α,5α,6-exo,6α)-3-(3,3-diMethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]Methyl]-benzaMide;CID 45115620;ML218;VU0413807;VU0424199-1;ML 218 hydrochloride
• CAS NO: 1346233-68-8
• Molecular Formula: C19H26Cl2N2O
• Molecular Weight: 369.32854
• Product Categories: Aromatics, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 1346233-68-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 455.5±35.0 °C(Predicted)
• Appearance: white to beige/
• Density: 1.184±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• Solubility: DMSO: soluble10mg/mL (clear solution)
• PKA: 13.65±0.46(Predicted)
• CAS DataBase Reference: 3,5-Dichloro-N-[[(1α,5α,6-exo,6α)-3-(3,3-diMethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]Methyl]-benzaMide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Dichloro-N-[[(1α,5α,6-exo,6α)-3-(3,3-diMethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]Methyl]-benzaMide(1346233-68-8)
• EPA Substance Registry System: 3,5-Dichloro-N-[[(1α,5α,6-exo,6α)-3-(3,3-diMethylbutyl)-3-azabicyclo[3.1.0]hex-6-yl]Methyl]-benzaMide(1346233-68-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 1346233-68-8(Hazardous Substances Data)

Usage

Description

3,5-dichloro-N-[[(1R,5S)-3-(3,3-dimethylbutyl)-3-azabicyclo[3.1.0]hexan-6-yl]methyl]benzamide, also known as ML218, is a complex organic compound characterized by its unique molecular structure. It is a centrally active calcium channel inhibitor, which suggests its potential role in modulating the activity of calcium channels in the central nervous system. This property makes ML218 a promising candidate for further research and development in the treatment of various conditions related to calcium channel dysregulation.

Uses

Used in Pharmaceutical Industry:
ML218 is used as a centrally active calcium channel inhibitor for the potential treatment of pain, epilepsy, and neurological disorders. Its ability to modulate calcium channels in the central nervous system makes it a valuable compound for further study and development in these therapeutic areas.
Used in Research Applications:
In addition to its potential therapeutic uses, ML218 may also be utilized in research settings to better understand the role of calcium channels in various physiological and pathological processes. This could lead to the discovery of new targets and mechanisms for the treatment of a wide range of conditions.
Used in Drug Development:
As a calcium channel inhibitor, ML218 may be further developed into a novel drug candidate for the treatment of pain, epilepsy, and neurological disorders. Its unique molecular structure and central activity make it an interesting starting point for the design of new drugs with improved efficacy, safety, and pharmacokinetic properties.