1346252-26-3Relevant articles and documents
Trifluoromethylation of heterocycles in water at room temperature
Fennewald, James C.,Lipshutz, Bruce H.
, p. 1097 - 1100 (2014)
Using a reaction medium containing nanoparticles consisting of commercially available TPGS-750-M in water, a combination of Langlois' reagent and t-BuOOH can be used to effect trifluoromethylation of several heterocyclic arrays, including heteroaromatics. These reactions take place at ambient temperatures, and the aqueous medium can be recycled.