1346253-45-9Relevant academic research and scientific papers
Asymmetric synthesis of O-alkylated tetronic acid derivatives via an organocatalytic Mannich reaction and subsequent intramolecular cyclization
Luo, Nian-Hua,Sun, Xiang,Yan, Yun-Yun,Nie, Shao-Zhen,Yan, Ming
, p. 1536 - 1541 (2011)
The organocatalytic asymmetric Mannich reaction of ethyl 4-chloro-3-oxobutanoate with N-Boc-imines has been studied and Cinchona alkaloids and chiral thiourea-tertiary amines were evaluated as catalysts. A pyrrolidine-based thiourea-tertiary amine was ide
