134627-50-2

Upstream product

• 32315-10-9 bis(trichloromethyl) carbonate 
• 5638-63-1 5,6-dihydro-4H-[1,3]oxazine 
• 201230-82-2 carbon monoxide 
• 99333-55-8 2-(4(S)-phenyloxazolidin-2-on-3-yl)acetyl chloride 

Downstream Products

• 151074-98-5 (S)-N-(3-Hydroxy-propyl)-2-methyl-3-oxo-2-((S)-2-oxo-4-phenyl-oxazolidin-3-yl)-propionamide 
• 151074-93-0 (+)-(2S)-Methyl 3-amino-2-methyl-2-<(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl>propanoate 
• 151074-83-8 (+)-(2S)-Methyl 2-methyl-2-<(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl>-3-oxopropanoate 
• 151074-92-9 (+)-(2S)-Methyl 3-(benzylamino)-2-methyl-2-<(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl>propanoate 
• 151075-00-2 (+)-(2S)-N-(3'-Hydroxypropyl)-3-hydroxy-2-methyl-2-<(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl>propionamide 
• 151075-02-4 (+)-(2S)-Dimethyl 2-methyl-2-<(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl>pentane-1,5-dioate 
• 151074-87-2 (+)-(2S)-Methyl 2-methyl-4-cyano-2-<(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl>butanoate 
• 151074-88-3 (S)-2-Methyl-2-((S)-2-oxo-4-phenyl-oxazolidin-3-yl)-pentanedioic acid 
• 151074-94-1 (+)-(2S)-Methyl 4,4-dibromo-2-methyl-2-<(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl>-3-butenoate 
• 151074-89-4 (S)-4-Cyano-2-methyl-2-((S)-2-oxo-4-phenyl-oxazolidin-3-yl)-butyric acid 
• 151074-95-2 (S)-4-Bromo-2-methyl-2-((S)-2-oxo-4-phenyl-oxazolidin-3-yl)-but-3-ynoic acid 
• 151074-90-7 (+)-(2S)-Methyl 2-methyl-2-<(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl>buten-3-oate 
• 151124-11-7 (+)-(6S,7S)-7-Methyl-7-<(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl>-1-aza-5-oxabicyclo<4.2.0>octan-8-one 

Relevant academic research and scientific papers

Asymmetric Synthesis of α-Alkyl-α-amino Acids from Chromium-Carbene-Complex-Derived β-Lactams

Optically active bicyclic β-lactam 3 was synthesized by photolysis of optically active oxazolidine carbene chromium complex 1 with oxazine 2.Conversion of the oxazolidine to the oxazolidinone gave a bicyclic β-lactam readily α-alkylated.Cleavage of the alkylated β-lactam gave optically active ester aldehyde 7, which was converted to a number of optically active α-alkyl-α-amino acids.These include (R)-α-methylserine, (S)-α-methylglutamic acid, (S)-α-methylornithine, (S)-vinylalanine, (S)-ethynylalanine, and (S)-2-methyl-2,3-diaminopropionic acid.