134637-14-2Relevant academic research and scientific papers
Ortho-(1-phenylvinyl)benzoate glycosylation donor, and preparation method and application thereof
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Paragraph 0103; 0107-0109; 0130-0131, (2020/05/01)
The invention discloses an ortho-(1-phenylvinyl)benzoate glycosylation donor, and a preparation method and an application thereof in a glycosylation reaction. The ortho-(1-phenylvinyl)benzoate glycosylation donor is stable, is easy to prepare and store, and is widely applied to the construction of various oxygen glucosides and nucleoside (nitrogen glucoside) glycosidic bonds. The leaving group ofthe donor is an alkenyl ester, has a high activity, and can be combined with thioglycoside or n-pentenyl ether glucoside through a one-pot glycosylation reaction to synthesize oligosaccharide. The glycosylation reaction conditions are mild, and receptors sensitive to acid and electrophilic reagents can tolerate the glycosylation reaction conditions.
A new and general glycosidation method for podophyllum lignan glycosides
Hashimoto, Shun-Ichi,Honda, Takeshi,Ikegami, Shiro
, p. 1653 - 1654 (2007/10/02)
A facile and stereocontrolled construction of β-glycosidic linkages of podophyllotoxin and 4′-O-demethylepipodophyllotoxin D-glucosides or 4′-O-demethylepipodophyllotoxin 2-amino-2-deoxy-D-glucoside has been achieved by exploiting glycopyranosyl P,P-diphenyl-N-(p-toluenesulfonyl)phosphinimidate and bis(dimethylamido) phosphate as glycosyl donors, respectively.
