1346508-81-3Relevant academic research and scientific papers
Copper-Catalyzed Asymmetric Propargylic Alkylation with Oxindoles: Diastereo- A nd Enantioselective Construction of Vicinal Tertiary and All-Carbon Quaternary Stereocenters
Xia, Jin-Tao,Hu, Xiang-Ping
supporting information, p. 1102 - 1107 (2020/02/15)
A copper-catalyzed asymmetric propargylic alkylation of propargylic acetates with 3-substituted oxindoles for the stereoselective construction of vicinal tertiary and all-carbon quaternary stereocenters in a 3,3-disubstituted oxindole skeleton has been realized. The reaction proceeded smoothly under the catalysis of Cu(MeCN)4PF6combined with a chiral tridentate ferrocenyl P,N,N ligand, leading to a broad range of optically active 3,3-disubstituted oxindoles in high yields and with excellent diastereo- A nd enantioselectivities.
Photoredox asymmetric catalytic enantioconvergent substitution of 3-chlorooxindoles
Jiang, Zhiyong,Li, Yunqiang,Qiao, Baokun,Zeng, Guangkuo,Zhao, Xiaowei
supporting information, p. 11362 - 11365 (2019/09/30)
An enantioconvergent substitution of 3-substituted 3-chlorooxindoles with N-aryl glycines under visible light irradiation is reported. A transition-metal-free cooperative catalysis platform with a dicyanopyrazine-derived chromophore (DPZ) as a photoredox catalyst and a chiral Br?nsted acid catalyst is effective for these transformations, which involve a single-electron transfer redox step and an enantioselective radical coupling. A variety of valuable chiral 3-aminomethylene-3-substituted oxindoles can be directly synthesized with high yields and enantioselectivities.
Copper-catalyzed arylation of indolin-2,3-ones with arylboronic acids
Zhang, Jilei,Chen, Jiuxi,Ding, Jinchang,Liu, Miaochang,Wu, Huayue
supporting information; experimental part, p. 9347 - 9351 (2011/12/14)
A convenient and efficient Cu(OTf)2-catalyzed arylation of indolin-2,3-ones with arylboronic acids using cheap 1,10-phenanthroline hydrate as ligand was developed under air atmosphere, achieving 3-aryl-3-hydroxy-2- oxindoles in good to excellen
Mo-catalyzed regio-, diastereo-, and enantioselective allylic alkylation of 3-aryloxindoles
Trost, Barry M.,Zhang, Yong
, p. 14548 - 14549 (2008/09/19)
A highly regio-, diastereo-, and enantioselective allylic alkylation reaction mediated by a chiral molybdenum catalyst has been developed as a novel entry into synthetically versatile 3-alkyl-3-aryloxindoles. Extremely bulky nucleophiles were employed to
