1346601-03-3
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Basic information
- Product Name: 3-Indoxyl Sulfate-d4 PotassiuM Salt
- Synonyms: 3-Indoxyl Sulfate-d4 PotassiuM Salt;1H-Indol-3-ol 3-(Hydrogen Sulfate)-d4 PotassiuM Salt;1H-Indol-3-ol Hydrogen Sulfate (Ester)-d4 MonopotassiuM Salt;Indol-3-ol PotassiuM Sulfate-d4;Indol-3-yl PotassiuM Sulfate-d4;Indol-3-yl Sulfate PotassiuM Salt-d4;PotassiuM Indol-3-yl Sulfate-d4
- CAS NO:1346601-03-3
- Molecular Formula: C8H5KNO4S
- Molecular Weight: 250.2929
- EINECS: N/A
- Product Categories: Agonists;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Pharmaceuticals;Sulfur & Selenium Compounds;Agonists, Aromatics, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
- Mol File: 1346601-03-3.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: Hygroscopic, Refrigerator, Under Inert Atmosphere
- Solubility: DMSO (Slightly), Methanol (Slightly)
- Stability: Hygroscopic
- CAS DataBase Reference: 3-Indoxyl Sulfate-d4 PotassiuM Salt(CAS DataBase Reference)
- NIST Chemistry Reference: 3-Indoxyl Sulfate-d4 PotassiuM Salt(1346601-03-3)
- EPA Substance Registry System: 3-Indoxyl Sulfate-d4 PotassiuM Salt(1346601-03-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1346601-03-3(Hazardous Substances Data)
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1346601-03-3 Usage
Description
3-Indoxyl Sulfate-d4 PotassiuM Salt, also known as 3-Indoxyl sulfate potassium salt, is a labeled uremic toxin that serves as a potent endogenous agonist for the human aryl hydrocarbon receptor (AHR). It is a white solid and has been identified as a sensitive and early biomarker of nephrotoxicity.Uses
Used in Pharmaceutical Industry:3-Indoxyl Sulfate-d4 PotassiuM Salt is used as a biomarker for nephrotoxicity, which is crucial in the development and testing of new drugs and therapies. Its ability to indicate early signs of kidney damage makes it a valuable tool in the assessment of potential drug toxicity.
Used in Research and Development:
In the field of research and development, 3-Indoxyl Sulfate-d4 PotassiuM Salt is used as a research compound to study the role of AHR in various biological processes and diseases. Its interaction with the aryl hydrocarbon receptor can provide insights into the underlying mechanisms of nephrotoxicity and other related conditions.
Used in Diagnostics:
3-Indoxyl Sulfate-d4 PotassiuM Salt is used as a diagnostic marker to detect and monitor kidney function in patients. Its sensitivity as an early indicator of nephrotoxicity makes it a valuable addition to the diagnostic tools available for assessing kidney health.
Used in Toxicology Studies:
In toxicology, 3-Indoxyl Sulfate-d4 PotassiuM Salt is used to evaluate the potential nephrotoxic effects of various substances, including chemicals, drugs, and environmental pollutants. This helps in understanding the risk factors associated with kidney damage and developing strategies to mitigate them.
Check Digit Verification of cas no
The CAS Registry Mumber 1346601-03-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,4,6,6,0 and 1 respectively; the second part has 2 digits, 0 and 3 respectively.Calculate Digit Verification of CAS Registry Number 1346601-03:
(9*1)+(8*3)+(7*4)+(6*6)+(5*6)+(4*0)+(3*1)+(2*0)+(1*3)=133
133 % 10 = 3
So 1346601-03-3 is a valid CAS Registry Number.
1346601-03-3Upstream product
1346601-03-3Downstream Products
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3-Indoxyl Sulfate-d4 PotassiuM Salt
