1346606-26-5

Basic information

• Product Name: all-trans 4-Keto Retinoic Acid-(9-Methyl)-d3
• Synonyms: all-trans 4-Keto Retinoic Acid-(9-Methyl)-d3;4-keto-Retinoic Acid-7-d3;4-Ketoretinoic Acid-7-d3;4-Oxo-all-trans-retinoic Acid-7-d3;4-Oxo-atRA-7-d3;4-Oxoretinoic Acid-7-d3;4-Oxotretinoin-d3;all-trans-4-Oxoretinoic Acid-7-d3
• CAS NO: 1346606-26-5
• Molecular Formula: C20H23D3O3
• Molecular Weight: 317.437125334
• Product Categories: Intermediates & Fine Chemicals;Isotope Labelled Compounds;Metabolites & Impurities;Pharmaceuticals;Retinoids
• Mol File: 1346606-26-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 178-180°C
• Appearance: /
• Storage Temp.: Amber Vial, -20°C Freezer, Under inert atmosphere
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• Stability: Light Sensitive
• CAS DataBase Reference: all-trans 4-Keto Retinoic Acid-(9-Methyl)-d3(CAS DataBase Reference)
• NIST Chemistry Reference: all-trans 4-Keto Retinoic Acid-(9-Methyl)-d3(1346606-26-5)
• EPA Substance Registry System: all-trans 4-Keto Retinoic Acid-(9-Methyl)-d3(1346606-26-5)

Safety Data

• Hazardous Substances Data: 1346606-26-5(Hazardous Substances Data)

Usage

Description

All-trans 4-Keto Retinoic Acid-(9-Methyl)-d3 is a deuterated metabolite of all-trans-Retinoic Acid, which serves as a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). It is a yellow solid with significant implications in various applications due to its interaction with these receptors.

Uses

Used in Pharmaceutical Industry:
All-trans 4-Keto Retinoic Acid-(9-Methyl)-d3 is used as a pharmaceutical compound for its ability to modulate the activity of RAR and RXR receptors. This interaction plays a crucial role in the development of treatments for various diseases, including certain types of cancer, as these receptors are involved in regulating gene expression and cell differentiation.
Used in Research and Development:
In the field of research and development, all-trans 4-Keto Retinoic Acid-(9-Methyl)-d3 is used as a research tool to study the functions and mechanisms of RAR and RXR receptors. This understanding can lead to the discovery of new therapeutic targets and the development of novel drugs for a range of conditions.
Used in Drug Synthesis:
All-trans 4-Keto Retinoic Acid-(9-Methyl)-d3 is also used as a key intermediate in the synthesis of other retinoid-based drugs. Its unique chemical properties make it a valuable building block for creating new compounds with potential therapeutic applications.
Used in Diagnostic Applications:
Due to its interaction with RAR and RXR receptors, all-trans 4-Keto Retinoic Acid-(9-Methyl)-d3 can be employed in the development of diagnostic tools and tests to assess the status of these receptors in various disease conditions. This can aid in the early detection and monitoring of diseases where these receptors play a significant role.