1346672-55-6Relevant articles and documents
Copper-catalyzed coupling of imidazoles and pyrazoles with 1,1-dibromo-1-alkenes: A distinct approach for direct N-alkynylation of heteroarenes
Das, Biswanath,Salvanna,Reddy, Gandolla Chinna,Balasubramanyam, Penagaluri
experimental part, p. 6497 - 6500 (2011/12/15)
The direct N-alkynylation of heteroarenes, imidazoles, and pyrazoles with 1,1-dibromo-1-alkene has been carried out for the first time using [Cu(Phen)PPh3Br] (as a catalyst) and Cs2CO3 in DMSO at 80 °C. The products are formed in good to high yields (66-85%) within 3 h. No side products could be detected.