1346751-51-6

Upstream product

• 141642-82-2 5-oxo-azepane-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester 
• 1443153-29-4 tert-butyl 2-(4-methylpiperazin-1-yl)-4-oxo-5,6,8,9-tetrahydro-3H-pyrimido[4,5-d]azepine-7(4H)-carboxylate 
• 1443153-40-9 tert-butyl 4-(4-fluorophenylamino)-2-(4-methylpiperazin-1-yl)-8,9-dihydro-5H-pyrimido[4,5-d]azepine-7(6H)-carboxylate 
• 109-01-3 1-methyl-piperazine 
• 79099-07-3 N-tert-butyloxycarbonylpiperidin-4-one 
• 45798-01-4 4-methyl piperazine-1-carboximidamide 

Downstream Products

• 1443153-21-6 N-(4-fluorophenyl)-7-methyl-2-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepin-4-amine 

Relevant academic research and scientific papers

Novel pyrimidoazepine analogs as serotonin 5-HT2A and 5-HT 2C receptor ligands for the treatment of obesity

Obesity is one of the most serious public health problems worldwide in the 21st century. Current therapeutic treatment for obesity is mostly focused on preventive measures involving dietary control and physical exercises in combination with anti-obesity m