1346758-69-7

Upstream product

• 1346758-66-4 1,7,7-trimethylbicyclo[2.2.1]hepta-2,5-diene-2,5-diyl bis(trifluoromethanesulfonate) 
• 123324-71-0 p-tert-butylphenylboronic acid 
• 10293-01-3 5-oxobornyl acetate 
• 10293-02-4 (1S,2R)-1-methyl-2-hydroxy-7,7-dimethyl-bicyclo[2.2.1]hept-5-one 
• 2758-63-6 (1S,4S)-1,7,7-trimethylbicyclo[2.2.1]heptane-2,5-dione 

Relevant academic research and scientific papers

Expanding the C1-symmetric bicyclo[2.2.1]heptadiene ligand family: Highly enantioselective synthesis of cyclic β-aryl-substituted carbonyl compounds

The efficient preparation of highly enantioenriched cyclic β-aryl-substituted carbonyl compounds has been achieved through the Rh I-catalyzed asymmetric 1,4-addition of an array of arylboronic acids to cyclic α,β-unsaturated carbonyl compounds. In the presence of 0.1 or 0.5 mol-% of the RhI/1g complex, the products of conjugate addition were isolated in 89 to 98%ee and in good to excellent yield.

Highly enantioselective rhodium-catalyzed asymmetric 1,4-addition reactions of arylboronic acids to acyclic α,β-unsaturated compounds: The formal synthesis of (-)-indatraline

It's do or diene: Stable chiral bicyclo[2.2.1]diene ligands were synthesized from (-)-5-oxobornyl acetate and utilized in the asymmetric 1,4-addition reaction of arylboronic acids with acyclic α,β- unsaturated compounds. Low catalytic loading of the compl