134691-71-7

Basic information

• Product Name: (1E,2E)-1,2-bis(3,4-dimethoxybenzylidene)hydrazine
• Synonyms: (1E,2E)-1,2-bis(3,4-dimethoxybenzylidene)hydrazine
• CAS NO: 134691-71-7
• Molecular Weight: 328.368
• Mol File: 134691-71-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: (1E,2E)-1,2-bis(3,4-dimethoxybenzylidene)hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: (1E,2E)-1,2-bis(3,4-dimethoxybenzylidene)hydrazine(134691-71-7)
• EPA Substance Registry System: (1E,2E)-1,2-bis(3,4-dimethoxybenzylidene)hydrazine(134691-71-7)

Safety Data

• Hazardous Substances Data: 134691-71-7(Hazardous Substances Data)

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 

Downstream Products

• 120-14-9 3,4-dimethoxy-benzaldehyde 

Relevant articles and documents

Aldazines in the Castagnoli-Cushman Reaction

Aldazines were employed in the Castagnoli-Cushman reaction of homophthalic anhydride for the first time. The reaction proved to be distinctly diastereoselective when conducted at room temperature in acetonitrile, yielding predominantly the kinetic cis -co

Solvent-free, [Et3NH][HSO4] catalyzed facile synthesis of hydrazone derivatives

In the present study, a library of hydrazone analogues 2(a-j) and 4(a-e) were synthesized, which were typically accessed via a solvent-free facile nucleophilic addition between hydrazine hydrate and appropriately substituted aromatic aldehydes 1(a-j) and 3-formylchromones 3(a-e). The molecular structure of compound (2f) was well supported by single crystal X-ray crystallographic analysis and also verified by DFT calculations. This new synthetic, eco-friendly, sustainable protocol resulted in a remarkable improvement in the synthetic efficiency (90-98% yield), high purity, using [Et3NH][HSO4] as a catalyst and an environmentally benign solvent eliminating the need for a volatile organic solvent and additional catalyst. This ionic liquid is air and water stable and easy to prepare from cheap amine and acid. The present methodology is a green protocol offering several advantages such as, excellent yield of products, minimizing production of chemical wastes, shorter reaction profile, mild reaction conditions, simple operational procedure, easy preparation of catalyst and its recyclability up to five cycles without any appreciable loss in catalytic activity. The optimization conditions carried out in the present study revealed that 20 mol% of ionic liquid catalyst under solvent-free condition at 120°C are the best conditions for the synthesis of hydrazone derivatives in excellent yields.

Selective protection of carbonyl compounds as azines and their facile regeneration

Carbonyl compounds with freshly prepared hydrazinium formate successfully yielded the corresponding azines in excellent yields. In turn, azines were deprotected to the corresponding carbonyls using triethylammonium chlorochromate chemoselectively. Copyright Taylor & Francis Group, LLC.