1347032-87-4Relevant academic research and scientific papers
Palladium-catalyzed benzylation of unprotected anthranilic acids with benzyl alcohols in water
Hikawa, Hidemasa,Yokoyama, Yuusaku
supporting information; experimental part, p. 6512 - 6515 (2012/02/02)
Palladium-catalyzed benzylation of unprotected anthranilic acids with benzyl alcohols in the presence of Pd(OAc)2 (5 mol %) and sodium diphenylphosphinobenzene-3-sulfonate (TPPMS, 10 mol %) in water at 120-C for 16 h gave only dibenzylated anthranilic acids in good yields. Water may play important roles for the smooth generation of the (?3-benzyl)palladium species by activation of the hydroxyl group of the benzyl alcohol. 2011 American Chemical Society.
