13472-60-1

Basic information

• Product Name: 2-METHOXY-3,5-DIBROMO-PYRIDINE
• Synonyms: 3,5-DIBROMO-2-METHOXYPYRIDINE;2-METHOXY-3,5-DIBROMO-PYRIDINE;2-METHOXY-5-PICOLINE (2-METHOXY-5-METHYLPYRIDINE);Pyridine, 3,5-dibroMo-2-Methoxy-;3,5-DibroMo-2-Methoxypyridine
• CAS NO: 13472-60-1
• Molecular Formula: C₆H₅Br₂NO
• Molecular Weight: 266.92
• Product Categories: Pyridine;Heterocycle-Pyridine series
• Mol File: 13472-60-1.mol
• Article Data: 10

Chemical Properties

• Melting Point: 46-51℃
• Boiling Point: 235.7°Cat760mmHg
• Flash Point: 96.3°C
• Appearance: /
• Density: 1.919g/cm³
• Vapor Pressure: 0.076mmHg at 25°C
• Refractive Index: 1.582
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Solubility: soluble in Methanol
• PKA: -1.31±0.20(Predicted)
• CAS DataBase Reference: 2-METHOXY-3,5-DIBROMO-PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHOXY-3,5-DIBROMO-PYRIDINE(13472-60-1)
• EPA Substance Registry System: 2-METHOXY-3,5-DIBROMO-PYRIDINE(13472-60-1)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-41-22
• Safety Statements: 26-36-45
• RIDADR: UN 2811
• WGK Germany: 1
• HazardClass: IRRITANT
• Hazardous Substances Data: 13472-60-1(Hazardous Substances Data)

Usage

General Description

2-Methoxy-3,5-dibromo-pyridine is a chemical compound with the molecular formula C6H5Br2NO. It is a pyridine derivative with two bromine atoms and a methoxy group attached to the pyridine ring. 2-METHOXY-3,5-DIBROMO-PYRIDINE is used in the synthesis of various pharmaceuticals and agrochemicals due to its unique chemical properties. It is also used as an intermediate in organic synthesis and in the development of new materials. Additionally, 2-methoxy-3,5-dibromo-pyridine is a potential building block for the production of various biologically active compounds. However, it is important to handle this chemical with care as it may pose health and environmental hazards.

InChI:InChI=1/C6H5Br2NO/c1-10-6-5(8)2-4(7)3-9-6/h2-3H,1H3

Upstream product

• 1628-89-3 2-methoxypyridine 
• 75806-85-8 2,3,5-tribromopyridine 
• 13472-85-0 2-methoxy-5-bromopyridine 
• 67-56-1 methanol 
• 13472-81-6 3,5-dibromo-2-hydroxypyridine 
• 74-88-4 methyl iodide 
• 13466-38-1 5-bromopyridin-2(1H)-one 

Downstream Products

• 103058-87-3 5-bromo-2-methoxypyridine-3-carboxaldehyde 
• 351410-47-4 (5-bromo-2-methoxy-pyridin-3-yl)-methanol 
• 332133-73-0 3-benzyl-5-bromo-2-methoxypyridine 

Relevant articles and documents

Nucleophile promoted gold redox catalysis with diazonium salts: C-Br, C-S and C-P bond formation through catalytic Sandmeyer coupling

Gold-catalyzed C-heteroatom (C-X) coupling reactions are evaluated without using sacrificial oxidants. Vital to the success of this methodology is the nucleophile-assisted activation of aryldiazonium salts, which could be an effective oxidant for converting Au(i) to Au(iii) even without the addition of an assisting ligand or photocatalyst. By accelerating the reaction kinetics to outcompete C-C homo-coupling or diazonium dediazoniation, gold-catalyzed Sandmeyer reactions were achieved with different nucleophiles, forming C-Br, C-S and C-P bonds in high yields and selectivities.

Arylpyridinone ITK inhibitors for treating inflammation and cancer

Disclosed herein are arylpyridinone compounds and compositions useful in the treatment of ITK mediated diseases, such as inflammation, having the structure of Formula (I): wherein Ar, R2, R4, R5, n and X are as defined in

HETEROARYL ANTAGONISTS OF PROSTAGLANDIN D2 RECEPTORS

Described herein are compounds that are antagonists of PGD2 receptors. Also described are pharmaceutical compositions that include the compounds described herein, and methods of using such antagonists of PGD2 receptors, alone or in combination with other compounds, for treating respiratory, cardiovascular, and other PGD2-dependent or PGD2-mediated conditions or diseases.