134745-45-2Relevant academic research and scientific papers
A CONVENIENT SYNTHESIS OF PYRROLE- AND N-AMINOPYRROLE-3-PROPIONATE ESTERS
Jacobi, Peter A.,Cai, Guolin
, p. 1103 - 1120 (2007/10/02)
Trisubstituted pyrroles having a substitution pattern found in many naturally occurring linear and macrocyclic tetrapyrroles have been prepared in a regiospecific fashion by a two step sequence involving Diels-Alder reaction of 2-oxo-3-butenoate esters (58) with 2-alkoxy-1,3-pentadiene derivatives (46), followed by ozonolysis and Paal-Knorr cyclization.
2-OXO-3-BUTENOATE ESTERS AS DIENOPHILES AND THEIR UTILITY IN A NOVEL SYNTHESIS OF PYRROLES
Jacobi, Peter A.,Cai, Guolin
, p. 1765 - 1768 (2007/10/02)
Trisubstituted pyrroles of type 8 have been prepared in a regiospecific fashion by a two step sequence involving Diels-Alder reaction of 2-oxo-3-butenoate esters 1 with 2-alkoxy-1,3-pentadiene derivatives 13, followed by ozonolysis and Paal-Knorr cyclization.
