134752-72-0

Basic information

• Product Name: ethyl 3-benzylbenzoate
• Synonyms: ethyl 3-benzylbenzoate
• CAS NO: 134752-72-0
• Molecular Weight: 240.302
• Mol File: 134752-72-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: ethyl 3-benzylbenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-benzylbenzoate(134752-72-0)
• EPA Substance Registry System: ethyl 3-benzylbenzoate(134752-72-0)

Safety Data

• Hazardous Substances Data: 134752-72-0(Hazardous Substances Data)

Upstream product

• 100-51-6 benzyl alcohol 
• 24398-88-7 ethyl 3-bromobenzoate 
• 55791-06-5 benzyl mesylate 
• 19362-89-1 N-benzyl-N,N,N-trimethylammonium 4-methylbenzenesulfonate 
• 4334-87-6 [3-(ethoxycarbonyl)phenyl]boronic acid 
• 1128-76-3 3-chloro-benzoic acid ethyl ester 
• 100-44-7 benzyl chloride 
• 448961-43-1 C₁₀H₁₁IO₂ 
• 603-33-8 triphenylbismuthane 

Relevant articles and documents

Nickel-Catalyzed Reductive Cross-Coupling of Benzyl Chlorides with Aryl Chlorides/Fluorides: A One-Pot Synthesis of Diarylmethanes

The first nickel-catalyzed, magnesium-mediated reductive cross-coupling between benzyl chlorides and aryl chlorides or fluorides is reported. A variety of diarylmethanes can be prepared in good to excellent yields in a one-pot manner using easy-to-access mixed PPh3/NHC Ni(II) complexes of Ni(PPh3)(NHC)Br2 (NHC = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene, IPr, 1a; 1,3-di-tert-butylimidazol-2-ylidene, ItBu, 1b) as catalyst precursors. Activation of polychloroarenes or chemoselective cross-coupling based on the difference in catalytic activity between 1a and 1b is used to construct oligo-diarylmethane motifs.

Palladium-Catalysed Cross-Coupling of Benzylammonium Salts with Boronic Acids under Mild Conditions

Herein, we give a full account of the development of the palladium-catalysed cross-coupling of benzylammonium salts with boronic acids. A range of benzylamine-derived quaternary ammonium salts can be coupled with boronic acids under relatively mild conditions. Our optimization has identified ligands that can be used to chemoselectively cross-couple at the ammonium in the presence of chlorides. We demonstrate that intramolecular palladium-catalysed C-H activation is also a viable pathway for the putative benzyl-Pd(II) intermediate obtained upon oxidative addition and have optimised this to obtain fluorene in good yield.

Cobalt-Catalyzed Reductive Cross-Coupling Between Benzyl Chlorides and Aryl Halides

A new protocol for the direct reductive cobalt-catalyzed arylation of benzyl chlorides has been developed in order to form functionalized diarylmethanes. A variety of reactive groups either on the aryl or the benzyl halide was employed. This represents the first cobalt-catalyzed reductive cross-coupling which does not require any ligand and pyridine. A reaction pathway is proposed involving a radical benzyl species. (Figure presented.).