1347737-40-9Relevant academic research and scientific papers
Synthesis of chiral sulfoximines derived from 3-aminoquinazolinones and their catalysis of enantioselective diethylzinc addition to aldehydes
Karabuga, Semistan,Cakici, Murat,Kazaz, Cavit,Sahin, Ertan,Kilic, Hamdullah,Ulukanli, Sabri
, p. 7887 - 7896 (2011/12/04)
A series of sulfoxides were sulfoximinated using oxidative addition of 3-aminoquinazolinones by lead tetraacetate in the presence of hexamethyldisilazane. They were applied for the first time in catalytic enantioselective addition to aromatic aldehydes with a product enantiopurity (ee) of 92% in the case of 2-methoxybenzaldehyde.
