13480-18-7 Usage
General Description
The chemical 2,6-Piperazinedione, 1,4-bis(phenylmethyl)- is commonly known as PIPERAZINEDIONE. It is a white solid with a molecular formula of C20H18N2O2. 2,6-Piperazinedione, 1,4-bis(phenylmethyl)- is used in the pharmaceutical industry as an intermediate for the synthesis of various drugs and pharmaceuticals. It is also used in the production of organic compounds and also can be used as a building block for other chemicals. Additionally, it has potential applications in the field of research and development for its chemical properties and reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 13480-18-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,4,8 and 0 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 13480-18:
(7*1)+(6*3)+(5*4)+(4*8)+(3*0)+(2*1)+(1*8)=87
87 % 10 = 7
So 13480-18-7 is a valid CAS Registry Number.
13480-18-7Relevant academic research and scientific papers
Single-step conversion of aliphatic, aromatic and heteroaromatic primary amines into piperazine-2,6-diones
Kruse, C. G.,Troost, J. J.,Cohen-Fernandes, P.,Linden, H. van der,Loon, J. D. van
, p. 303 - 310 (2007/10/02)
The development of a facile, single-step method for the synthesis of 1,4-disubstituted piperazine-2,6-diones (4) in excellent yields from the corresponding aliphatic, aromatic and heteroaromatic primary amines and iminodiacetic acids (1) is described.A possible mechanism is discussed and the presence of intermediate 6a is confirmed by high-resolution proton NMR spectroscopy.The subsequent two-step conversion of dione 4a into the deoxygenated 4-unsubstituted piperazine 10 in high yield provides an attractive alternative to the currently available (hetero)arylpiperazine synthetic methods.
