134810-30-3Relevant academic research and scientific papers
Oxidation of mixtures of thioureas: Part XI - Oxidation of mixtures of 1-alkyl-3-arylthioureas and thiourea and study of steric influence around aryl groups on formation of 1,2,4-thiadiazolines
Joshua, C P,Sujatha, T S
, p. 600 - 603 (2007/10/02)
Hydrogen peroxide oxidation of a mixture of 1-alkyl-3-arylthiourea and thiourea in acidic alcoholic solution yields two isomeric 3-amino-1,2,4-thiadiazolines (VI and VII) via amidinothiourea.The rearrangement of the intermediate bis(formamidine)sulphide to the amidinothiourea derivative has been found to be governed by the steric effect.
