134822-78-9 Usage
Properties & Specific Content of 1-hydroxy-1-[(6-phenoxy-2H-chromen-3-yl)methyl]urea
A compound composed of 19 carbon atoms, 16 hydrogen atoms, 2 nitrogen atoms, and 4 oxygen atoms.
Urea Derivative
A chemical compound that has a structure similar to urea, with modifications that can enhance its biological activity.
Phenoxy-2H-chromen-3-ylmethyl group
A specific functional group within the compound that consists of a phenyl ring connected to a chromene ring through an oxygen atom.
Hydroxyurea group
A functional group within the compound that contains an oxygen atom bonded to two hydrogen atoms and a urea group.
Biological Activities
The compound exhibits various beneficial effects on biological systems, such as anti-tumor, anti-inflammatory, and anti-viral properties.
Dihydrofolate Reductase Inhibitor
The compound has been documented as an inhibitor of the enzyme dihydrofolate reductase, which is involved in the synthesis of nucleotides. Inhibition of this enzyme can disrupt the growth of cancer cells, making it a potential candidate for anti-cancer therapy.
Potential Anti-Cancer Therapy
Due to its dihydrofolate reductase inhibitory activity, 1-hydroxy-1-[(6-phenoxy-2H-chromen-3-yl)methyl]urea may be developed as a therapeutic agent for cancer treatment.
Potential Antiviral Drug Development
Studies have suggested that the compound possesses potential anti-viral properties, making it a candidate for the development of antiviral drugs.
Therapeutic Applications
1-hydroxy-1-[(6-phenoxy-2H-chromen-3-yl)methyl]urea has potential applications in the medical field due to its biologically active nature and various beneficial effects on biological systems.
Check Digit Verification of cas no
The CAS Registry Mumber 134822-78-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,8,2 and 2 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 134822-78:
(8*1)+(7*3)+(6*4)+(5*8)+(4*2)+(3*2)+(2*7)+(1*8)=129
129 % 10 = 9
So 134822-78-9 is a valid CAS Registry Number.
134822-78-9Relevant articles and documents
Substituted chromenes as potent, orally active 5-lipoxygenase inhibitors
Satoh,Stanton,Hutchison,Libby,Kowalski,Lee,White,Kimble
, p. 3580 - 3594 (2007/10/02)
A series of chromene derivatives was synthesized and evaluated for their in vitro and ex vivo 5-lipoxygenase (5-LO) inhibitory activity. These compounds were prepared by condensation of appropriate salicyl aldehydes with α,β-unsaturated carbonyl compounds
