13484-40-7Relevant articles and documents
N - alkylpiperazine purification of
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Paragraph 0056, (2017/02/28)
PROBLEM TO BE SOLVED: To provide a purification method of N-alkyl piperazines, capable of providing high purity N-alkyl piperazines with low cost and having a high recovery rate.SOLUTION: A mixture of N-alkyl piperazines and a piperazine is distilled in the presence of a polar organic solvent having a higher boiling point than that of the piperazine.
2,5-Disubstituted pyridines as potent GPR119 agonists
Wu, Yulin,Kuntz, Judith D.,Carpenter, Andrew J.,Fang, Jing,Sauls, Howard R.,Gomez, Daniel J.,Ammala, Carina,Xu, Yun,Hart, Shane,Tadepalli, Sarva
scheme or table, p. 2577 - 2581 (2010/06/19)
A series of 2-piperazinyl-5-alkoxypyridines were synthesized and screened against human GPR119 receptor. Through SAR analysis, compounds containing 2-alkylsulfonylpiperazinyl-5-alkoxypyridines were discovered and found to be potent agonists of the human GPR119 receptor.
Pyrrolidinone derivatives
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, (2008/06/13)
Since a compound represented by general formula (1), its pharmaceutically acceptable salt and a hydrate of the pharmaceutically acceptable salt have high antipsychotic activity, they may be used as an active ingredient for preparation of an antipsychotic. STR1 Also provided are an optical resolution method of the above compound and an intermediate for preparation of the compound.