13484-51-0

Basic information

• Product Name: 3,5,6-trichloropyrazin-2-aMine
• Synonyms: 3,5,6-trichloropyrazin-2-aMine;trichloropyrazin-2-amine
• CAS NO: 13484-51-0
• Molecular Formula: C4H2Cl3N3
• Molecular Weight: 198.43778
• EINECS: -0
• Mol File: 13484-51-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,5,6-trichloropyrazin-2-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5,6-trichloropyrazin-2-aMine(13484-51-0)
• EPA Substance Registry System: 3,5,6-trichloropyrazin-2-aMine(13484-51-0)

Safety Data

• Hazardous Substances Data: 13484-51-0(Hazardous Substances Data)

Upstream product

• 5049-61-6 2-Aminopyrazine 
• 52173-59-8 2,6-diamino-3,5-dinitro-pyrazine 
• 33332-28-4 2-amino-6-chloropyrazine 

Downstream Products

• 1427500-77-3 N-benzyl-2-amino-5,6-dichlorothiazolo[4,5-b]pyrazine 

Relevant articles and documents

Nitro derivatives of 2,1,3-benzothiadiazole 1-oxides: synthesis, structural study, and NO release

A convenient one-pot synthesis of nitro derivatives of 2,1,3-benzothiadiazole 1-oxides by the reaction of o-nitroanilines with sulfur monochloride was developed. The structural features of 4-nitrobenzothiadiazole and its N-oxide were considered. High in vitro release of nitric oxide (69%) was found for a 6-nitro-2,1,3-benzothiadiazole sample by the Griess assay, which indicated good prospects for this class of compounds.

Preparation technology of 2-bromo-3,5,6-trichloropyrazine

The invention discloses a preparation technology of 2-bromo-3,5,6-trichloropyrazine. The preparation technology comprises the following steps of using 2,6-dichloropyrazine as an initiating raw material, and performing ammoniation, halogenation and Sandmeyer reaction, so as to obtain a target compound, namely 2-bromo-3,5,6-trichloropyrazine. The preparation technology has the advantages that by adopting the synthesis route, the obtaining of raw materials is easy, the cost is low, the operation is simple, the product can be easily separated, the selectivity is high, the yield is higher, the total yield can reach 62.7%, and the preparation technology is favorable for actual application.