Axitinib Impurity b, also known as Axitinib Sulfone, is an impurity found in Axitinib (A794650), which is a tyrosine kinase inhibitor used in cancer therapy. It is characterized by its chemical structure, where it differs from the main compound by the presence of a sulfonyl group instead of a carbonyl group.
1348536-59-3
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Basic information
- Product Name: Axitinib Impurity b
- Synonyms: Axitinib Impurity b;Axitinib Sulfone
- CAS NO:1348536-59-3
- Molecular Formula: C22H18N4O3S
- Molecular Weight: 418.46832
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1348536-59-3.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Axitinib Impurity b(CAS DataBase Reference)
- NIST Chemistry Reference: Axitinib Impurity b(1348536-59-3)
- EPA Substance Registry System: Axitinib Impurity b(1348536-59-3)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1348536-59-3(Hazardous Substances Data)
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1348536-59-3 Usage
Uses
Used in Pharmaceutical Industry:Axitinib Impurity b is used as a reference compound for the development and quality control of axitinib (A794650) in the pharmaceutical industry. Its presence in the final product needs to be monitored and controlled to ensure the safety and efficacy of the drug.
Used in Cancer Research:
Axitinib Impurity b serves as a research tool in cancer research, particularly in the study of tyrosine kinase inhibitors and their mechanisms of action. Understanding the properties and effects of this impurity can contribute to the optimization of axitinib's therapeutic potential and the development of new cancer treatments.
Used in Drug Safety Assessment:
Axitinib Impurity b is used in drug safety assessment to evaluate the potential side effects and toxicological profile of axitinib. This helps in determining the acceptable levels of impurities in the final drug product and ensuring patient safety during treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 1348536-59-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,4,8,5,3 and 6 respectively; the second part has 2 digits, 5 and 9 respectively.Calculate Digit Verification of CAS Registry Number 1348536-59:
(9*1)+(8*3)+(7*4)+(6*8)+(5*5)+(4*3)+(3*6)+(2*5)+(1*9)=183
183 % 10 = 3
So 1348536-59-3 is a valid CAS Registry Number.
1348536-59-3Upstream product
1348536-59-3Downstream Products
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Axitinib Impurity b
