13487-63-3Relevant academic research and scientific papers
Direct Synthesis of Carboxylic Acids from Organoboranes
Hara, Shoji,Kishimura, Kotaro,Suzuki, Akira,Dhillon, Ranjit S.
, p. 6356 - 6360 (2007/10/02)
Direct Synthesis of carboxylic acids through a two carbon atom homologation from organoboranes has been achieved, by the reaction with the dianion of phenoxyacetic acid.It is now possible to synthesize alkanoic, alkenoic, or alkynoic acids, from the corresponding alkenes, dienes, or enynes, respectively, via hydroboration.The reaction is tolerant of various functional groups present in alkenes, thus giving the corresponding carboxylic acids with chloro, sulfide, ether, acetal, and thioacetal functionalities in good yields.
