134872-90-5Relevant academic research and scientific papers
N-(1'-Benzotriazolylmethyl)-5-phenylmorpholin-2-one: A stable crystalline chiral azomethine ylid precursor
Aldous,Hamelin,Harwood,Thurairatnam
, p. 1841 - 1842 (2007/10/03)
The crystalline adduct of (5S)-5-phenylmorpholin-2-one with formaldehyde and benzotriazole on treatment with acid generates an azomethine ylid which may be trapped with a range of dipolarophiles in yields superior to those using in situ generation methodology.
Development of chiral stabilised azomethine ylids: A chiral memory relay system
Anslow,Harwood,Phillips,Watkin,Wong
, p. 1343 - 1358 (2007/10/02)
Chiral, stabilised azomethine ylids incorporated in cyclic templates derived from (R)- or (S)-2-phenylglycinol and (S)-valine undergo enantioselective 1,3-dipolar cycloaddition reactions with a variety of dipolarophiles. Removal of the template in the cas
Development of a chiral stabilised azomethine ylid. A chiral relay system
Anslow,Harwood,Phillips,Watkin
, p. 169 - 172 (2007/10/02)
The chiral, stabilised azomethine ylids (2) derived from (R)-2-phenylglycinol has been demonstrated to undergo enantioselective 1,3-dipolar cycloaddition reactions with a range of alkene and alkyne dipolarophiles.
