134879-88-2

Upstream product

• 1655-07-8 ethyl 2-oxocyclohexane carboxylate 
• 63126-47-6 (2S)-2-(methoxymethyl)-1-pyrrolidine 
• 102069-84-1 (S)-2-methoxy-1-[[2'-(methoxymethyl)pyrrolidinyl]carbonyl]benzene 
• 546-67-8 lead(IV) tetraacetate 

Downstream Products

• 134879-89-3 (2R/S,2'S,3R/S)-2-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-3-methylcyclohexan-1-one 
• 140875-21-4 (1S,2S,2'S)-1-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-2-hydroxycyclohexan-1-ol 
• 140875-18-9 (2S,2'S)-2-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-2-hydroxycyclohexan-1-one 
• 140875-20-3 (1S,2S,2'S,6R)-1-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-2-hydroxy-6-(phenylseleno)cyclohexan-1-ol 
• 134880-12-9 (2S)-2-(methoxymethyl)pyrrolidine p-toluenesulfonate 
• 134880-11-8 (4S)-1-methyl-4,5,6,7-tetrahydro-4-phenyl-2,1-benzisoxazolin-3-one 
• 134879-90-6 4,5,6,7-tetrahydro-4-phenyl-2,1-benzisoxazol-3(3aH)-one 
• 134879-91-7 4,5,6,7-tetrahydro-4-phenyl-2,1-benzisoxazolin-3(1H)-one 
• 20795-53-3 (R)-3-phenylcyclohexanone 
• 134880-00-5 (2R/S,2'S,3R/S)-2-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-3-phenylcyclohexan-1-one 
• 134932-81-3 (2R,2'S,3R)-2-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-3-phenylcyclohexan-1-one 
• 134932-79-9 (2S,2'S,3S)-2-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-3-phenylcyclohexan-1-one 
• 134880-13-0 (1R/S,2'S)-2-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-1-phenylcyclohex-2-en-1-ol 
• 134879-97-3 (2R/S,2'S,3R/S)-2-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-3-propylcyclohexan-1-one 

Relevant academic research and scientific papers

Dehydrogenations with lead tetraacetate. Ketone to enone transformations in the 2-(aminocarbonyl)- and 2-(carbalkoxy)cycloalkanone series

Cyclic β-ketoesters and β-ketoamides are converted to 2-(carbalkoxy)- and 2-(aminocarbonyl)-2-cycloalken-1-ones by treatment with Pb(OAc)4 and Cu(OAc)2 in benzene.

Asymmetric syntheses of 3-substituted-cyclohexanone derivatives by stereoselective conjugate addition to chiral 2-substituted-2-cyclohexen-1-ones

Chiral 2-substituted-2-cyclohexen-1-one 2a is prepared from 1a by Birch reduction followed by acid-catalyzed hydrolysis-olefin migration. Conjugate additions of organometallic reagents to 2a occur with good to excellent diastereoselectivities (Table I). E