134889-04-6

Basic information

• Product Name: ETHYL 4-[(4-CHLOROANILINO)CARBONYL]-5-METHYL-3-ISOXAZOLECARBOXYLATE
• Synonyms: ETHYL 4-[(4-CHLOROANILINO)CARBONYL]-5-METHYL-3-ISOXAZOLECARBOXYLATE
• CAS NO: 134889-04-6
• Molecular Formula: C14H13ClN2O4
• Molecular Weight: 308.72
• Mol File: 134889-04-6.mol
• Article Data: 1

Chemical Properties

• Melting Point: 108-110°C
• Appearance: /
• CAS DataBase Reference: ETHYL 4-[(4-CHLOROANILINO)CARBONYL]-5-METHYL-3-ISOXAZOLECARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 4-[(4-CHLOROANILINO)CARBONYL]-5-METHYL-3-ISOXAZOLECARBOXYLATE(134889-04-6)
• EPA Substance Registry System: ETHYL 4-[(4-CHLOROANILINO)CARBONYL]-5-METHYL-3-ISOXAZOLECARBOXYLATE(134889-04-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 134889-04-6(Hazardous Substances Data)

Relevant articles and documents

4-isoxazolecarboxamide derivatives

This invention is directed to compounds of the formula (I): STR1 wherein R1 is --OR4 (where R4 is hydrogen, lower alkyl, lower hydroxyalkyl, phenyl, phenyl-lower-alkyl, or --(CH2)n Y where n is an integer from 1 to 4 and Y is morpholino, -SR5, --C(O)OR5, --C(O)N(R6)2, --N(R6)2, or --N+ (R6)3 X-, in which R5 is lower alkyl, each R6 is independently selected from hydrogen or lower alkyl, and X is halogen) or --SR7 (where R7 is lower alkyl, phenyl-lower-alkyl, or --(CH2)n W where W is --N(R6)2 or --N+ (R6)3 X-, and n, R6 and X are as previously defined); R2 is lower alkyl, phenyl or phenyl-lower-alkyl; R3 is halo, hydroxy, lower alkyl, lower alkoxy, lower haloalkyl, lower haloalkoxy, or --C(O)OR5 where R5 is as previously defined; and Z is a bond, 2,5-thienyl or 2,5-furanyl; or a pharmaceutically acceptable salt thereof. These compounds are useful in treating inflammation, autoimmune disease or allograft rejection in mammals.