134890-54-3

Basic information

• Product Name: 2-(4-cholorophenyl)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one
• Synonyms: 2-(4-cholorophenyl)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one
• CAS NO: 134890-54-3
• Molecular Weight: 300.768
• Mol File: 134890-54-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(4-cholorophenyl)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-cholorophenyl)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one(134890-54-3)
• EPA Substance Registry System: 2-(4-cholorophenyl)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one(134890-54-3)

Safety Data

• Hazardous Substances Data: 134890-54-3(Hazardous Substances Data)

Upstream product

• 33512-03-7 3-(4-chlorophenyl)oxirane-2,2-dicarbonitrile 
• 134469-07-1 Benzimidazol-2-thiol 

Relevant articles and documents

Regioselective ring opening of 2,2-dicyanooxiranes by 1,3-dinucleophiles in the presence of Lewis acids such as bismuth(III) nitrate pentahydrate [Bi(NO3)3·5H2O] and zirconium(IV) chloride (ZrCl4)

Bismuth(III) nitrate pentahydrate [Bi(NO3)3·5H2O] or zirconium(IV) chloride (ZrCl4) has been shown to catalyze nucleophilic ring opening of 2,2-dicyanooxiranes along with ring closure by 1,3-dinucleophiles such

Reaction of cyanoepoxides with 2-mercaptobenzimidazole and 2-aminothiazole and biological assessment of products formed

The two carbons of the epoxide ring of the gem-dicyano epoxides and α-cyano α-ester epoxides act as electrophilic centers when these compounds are reacted with 2-mercaptobenzimidazole. The reaction leads to 2,3-dihydrobenzimidazo[2,1-b]-thiazoles. However, such a reactivity of the epoxides is not observed during their reaction with 2-aminothiazoline. Some of the synthetized compounds showed anthelminthic properties.